U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SMG6 SMG6 nonsense mediated mRNA decay factor [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105584052, updated on 13-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
SMG6
Gene description
SMG6 nonsense mediated mRNA decay factor
See related
Ensembl:ENSCATG00000031956
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SMG6 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012000250.1 (13662758..13906764)

NW_012000250.1Genomic Context describing neighboring genes Neighboring gene small G protein signaling modulator 2 Neighboring gene TSR1 ribosome maturation factor Neighboring gene serine racemase Neighboring gene uncharacterized LOC105584075 Neighboring gene mitochondrial calcium uniporter regulator 1 pseudogene Neighboring gene HIC ZBTB transcriptional repressor 1 Neighboring gene OVCA2 serine hydrolase domain containing Neighboring gene diphthamide biosynthesis 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_012000250.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomerase RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of telomerase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
telomerase-binding protein EST1A

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012000250.1 Reference Caty_1.0

    Range
    13662758..13906764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012056426.1 → XP_011911816.1  telomerase-binding protein EST1A isoform X1

    UniProtKB/TrEMBL
    A0A2K5LSW2
    Related
    ENSCATP00000016039.1, ENSCATT00000040196.1
    Conserved Domains (5) summary
    cd09885
    Location:1241 → 1416
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    sd00006
    Location:765 → 795
    TPR; TPR repeat [structural motif]
    pfam05750
    Location:350 → 538
    Rubella_Capsid; Rubella capsid protein
    pfam10373
    Location:751 → 1103
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:638 → 741
    EST1; Telomerase activating protein Est1

  2. XM_012056445.1 → XP_011911835.1  telomerase-binding protein EST1A isoform X2

    See identical proteins and their annotated locations for XP_011911835.1

    Conserved Domains (5) summary
    cd09885
    Location:1210 → 1385
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    sd00006
    Location:734 → 764
    TPR; TPR repeat [structural motif]
    pfam05750
    Location:319 → 507
    Rubella_Capsid; Rubella capsid protein
    pfam10373
    Location:720 → 1072
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:607 → 710
    EST1; Telomerase activating protein Est1

  3. XM_012056434.1 → XP_011911824.1  telomerase-binding protein EST1A isoform X2

    See identical proteins and their annotated locations for XP_011911824.1

    Conserved Domains (5) summary
    cd09885
    Location:1210 → 1385
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    sd00006
    Location:734 → 764
    TPR; TPR repeat [structural motif]
    pfam05750
    Location:319 → 507
    Rubella_Capsid; Rubella capsid protein
    pfam10373
    Location:720 → 1072
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:607 → 710
    EST1; Telomerase activating protein Est1

  4. XM_012056455.1 → XP_011911845.1  telomerase-binding protein EST1A isoform X3

    Conserved Domains (1) summary
    cd09885
    Location:154 → 329
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs

RNA

  1. XR_001014360.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.