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SPTLC1 serine palmitoyltransferase long chain base subunit 1 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105578733, updated on 13-Mar-2024

Summary

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Gene symbol
SPTLC1
Gene description
serine palmitoyltransferase long chain base subunit 1
See related
Ensembl:ENSCATG00000030234
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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See SPTLC1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012000030.1 (1759147..1833366, complement)

NW_012000030.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105578721 Neighboring gene 60S ribosomal protein L21 pseudogene Neighboring gene spermatogenesis-associated protein 31E1-like Neighboring gene spermatogenesis-associated protein 31E1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012000030.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine C-palmitoyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine palmitoyltransferase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012000030.1 Reference Caty_1.0

    Range
    1759147..1833366 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012044817.1 → XP_011900207.1  serine palmitoyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A2K5LGM6, A0A2K5LGR2
    Related
    ENSCATP00000012128.1, ENSCATT00000036256.1
    Conserved Domains (2) summary
    COG0156
    Location:93 → 467
    BioF; 7-keto-8-aminopelargonate synthetase or related enzyme [Coenzyme transport and metabolism]
    cl18945
    Location:11 → 472
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

  2. XM_012044844.1 → XP_011900234.1  serine palmitoyltransferase 1 isoform X3

    See identical proteins and their annotated locations for XP_011900234.1

    UniProtKB/TrEMBL
    A0A2K5LGR2
    Related
    ENSCATP00000012145.1, ENSCATT00000036273.1
    Conserved Domains (1) summary
    cl18945
    Location:11 → 452
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

  3. XM_012044831.1 → XP_011900221.1  serine palmitoyltransferase 1 isoform X2

    Related
    ENSCATP00000012154.1, ENSCATT00000036282.1
    Conserved Domains (1) summary
    cl18945
    Location:11 → 147
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

RNA

  1. XR_001012529.1 RNA Sequence

  2. XR_001012530.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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