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TMTC4 transmembrane O-mannosyltransferase targeting cadherins 4 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105574439, updated on 13-Mar-2024

Summary

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Gene symbol
TMTC4
Gene description
transmembrane O-mannosyltransferase targeting cadherins 4
See related
Ensembl:ENSCATG00000017163
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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See TMTC4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012003834.1 (5914235..5983854)

NW_012003834.1Genomic Context describing neighboring genes Neighboring gene sodium leak channel, non-selective Neighboring gene uncharacterized LOC105574438 Neighboring gene uncharacterized LOC105574444 Neighboring gene gamma-glutamylamine cyclotransferase Neighboring gene propionyl-CoA carboxylase subunit alpha Neighboring gene 60S ribosomal protein L15 pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012003834.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transmembrane and TPR repeat-containing protein 4
Names
transmembrane and tetratricopeptide repeat containing 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012003834.1 Reference Caty_1.0

    Range
    5914235..5983854
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012035372.1 → XP_011890762.1  transmembrane and TPR repeat-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A2K5KWU3
    Related
    ENSCATP00000005116.1, ENSCATT00000019609.1
    Conserved Domains (7) summary
    smart00028
    Location:667 → 700
    TPR; Tetratricopeptide repeats
    COG0457
    Location:564 → 824
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:565 → 593
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:633 → 666
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:565 → 598
    TPR_2; Tetratricopeptide repeat
    pfam08409
    Location:375 → 449
    DUF1736; Domain of unknown function (DUF1736)
    pfam13431
    Location:587 → 620
    TPR_17; Tetratricopeptide repeat

  2. XM_012035375.1 → XP_011890765.1  transmembrane and TPR repeat-containing protein 4 isoform X3

    UniProtKB/TrEMBL
    A0A2K5KWR6
    Related
    ENSCATP00000005123.1, ENSCATT00000019638.1
    Conserved Domains (6) summary
    COG0457
    Location:481 → 754
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:482 → 510
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:550 → 583
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:482 → 515
    TPR_2; Tetratricopeptide repeat
    pfam08409
    Location:292 → 366
    DUF1736; Domain of unknown function (DUF1736)
    pfam13431
    Location:504 → 537
    TPR_17; Tetratricopeptide repeat

  3. XM_012035373.1 → XP_011890763.1  transmembrane and TPR repeat-containing protein 4 isoform X2

    See identical proteins and their annotated locations for XP_011890763.1

    Conserved Domains (6) summary
    COG0457
    Location:500 → 773
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:501 → 529
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:569 → 602
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:501 → 534
    TPR_2; Tetratricopeptide repeat
    pfam08409
    Location:311 → 385
    DUF1736; Domain of unknown function (DUF1736)
    pfam13431
    Location:523 → 556
    TPR_17; Tetratricopeptide repeat

  4. XM_012035376.1 → XP_011890766.1  transmembrane and TPR repeat-containing protein 4 isoform X4

    Conserved Domains (6) summary
    COG0457
    Location:469 → 742
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:470 → 498
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:538 → 571
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:470 → 503
    TPR_2; Tetratricopeptide repeat
    pfam08409
    Location:280 → 354
    DUF1736; Domain of unknown function (DUF1736)
    pfam13431
    Location:492 → 525
    TPR_17; Tetratricopeptide repeat

  5. XM_012035374.1 → XP_011890764.1  transmembrane and TPR repeat-containing protein 4 isoform X2

    See identical proteins and their annotated locations for XP_011890764.1

    Conserved Domains (6) summary
    COG0457
    Location:500 → 773
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:501 → 529
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:569 → 602
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:501 → 534
    TPR_2; Tetratricopeptide repeat
    pfam08409
    Location:311 → 385
    DUF1736; Domain of unknown function (DUF1736)
    pfam13431
    Location:523 → 556
    TPR_17; Tetratricopeptide repeat

  6. XM_012035377.1 → XP_011890767.1  transmembrane and TPR repeat-containing protein 4 isoform X5

    Related
    ENSCATP00000005159.1, ENSCATT00000019735.1
    Conserved Domains (6) summary
    sd00006
    Location:361 → 389
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:429 → 462
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:361 → 394
    TPR_2; Tetratricopeptide repeat
    pfam08409
    Location:171 → 245
    DUF1736; Domain of unknown function (DUF1736)
    pfam13414
    Location:360 → 426
    TPR_11; TPR repeat
    pfam13431
    Location:383 → 416
    TPR_17; Tetratricopeptide repeat
Nucleotide Protein
Heading Accession and Version

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