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PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105573658, updated on 13-Mar-2024

Summary

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Gene symbol
PFKFB4
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
See related
Ensembl:ENSCATG00000038306
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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See PFKFB4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012003502.1 (4301578..4338164, complement)

NW_012003502.1Genomic Context describing neighboring genes Neighboring gene ATR interacting protein Neighboring gene three prime repair exonuclease 1 Neighboring gene shisa family member 5 Neighboring gene collagen type VII alpha 1 chain Neighboring gene urocortin 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012003502.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012003502.1 Reference Caty_1.0

    Range
    4301578..4338164 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012033565.1 → XP_011888955.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X3

    See identical proteins and their annotated locations for XP_011888955.1

    UniProtKB/TrEMBL
    A0A2K5MY95
    Related
    ENSCATP00000030212.1, ENSCATT00000054474.1
    Conserved Domains (2) summary
    cd07067
    Location:252 → 402
    HP_PGM_like; Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction
    pfam01591
    Location:35 → 249
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_012033562.1 → XP_011888952.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X1

    See identical proteins and their annotated locations for XP_011888952.1

    UniProtKB/TrEMBL
    A0A2K5MYD9
    Related
    ENSCATP00000030216.1, ENSCATT00000054478.1
    Conserved Domains (2) summary
    pfam00300
    Location:252 → 438
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 249
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_012033564.1 → XP_011888954.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X2

    See identical proteins and their annotated locations for XP_011888954.1

    Conserved Domains (2) summary
    pfam01591
    Location:1 → 215
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:218 → 401
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  4. XM_012033566.1 → XP_011888956.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X4

    See identical proteins and their annotated locations for XP_011888956.1

    UniProtKB/TrEMBL
    A0A2K5MYR5
    Related
    ENSCATP00000030220.1, ENSCATT00000054482.1
    Conserved Domains (2) summary
    pfam01591
    Location:35 → 249
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:252 → 364
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
Nucleotide Protein
Heading Accession and Version

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