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LTA4H leukotriene A4 hydrolase [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105573420, updated on 13-Mar-2024

Summary

Gene symbol
LTA4H
Gene description
leukotriene A4 hydrolase
See related
Ensembl:ENSCATG00000043659
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
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Genomic context

See LTA4H in Genome Data Viewer
Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012003393.1 (17294403..17331529)

NW_012003393.1Genomic Context describing neighboring genes Neighboring gene ETS transcription factor ELK3 Neighboring gene uncharacterized LOC105573357 Neighboring gene histidine ammonia-lyase Neighboring gene amidohydrolase domain containing 1

Genomic regions, transcripts, and products

Genomic Sequence:
NW_012003393.1 Unplaced Scaffold Reference Caty_1.0

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aminopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables epoxide hydrolase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables leukotriene-A4 hydrolase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in leukotriene biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in peptide catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012003393.1 Reference Caty_1.0

    Range
    17294403..17331529
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012032926.1XP_011888316.1  leukotriene A-4 hydrolase

    UniProtKB/TrEMBL
    A0A2K5NXN2
    Related
    ENSCATP00000042155.1, ENSCATT00000066588.1
    Conserved Domains (3) summary
    cd09599
    Location:6438
    M1_LTA4H; Peptidase M1 family contains leukotriene A4 hydrolase
    TIGR02411
    Location:6596
    leuko_A4_hydro; leukotriene A-4 hydrolase/aminopeptidase
    pfam09127
    Location:456595
    Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal