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PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [ Mandrillus leucophaeus (drill) ]

Gene ID: 105548115, updated on 13-Mar-2024

Summary

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Gene symbol
PFKFB1
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
See related
Ensembl:ENSMLEG00000040347
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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See PFKFB1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012104255.1 (173721..233282)

NW_012104255.1Genomic Context describing neighboring genes Neighboring gene PAGE family member 2B Neighboring gene 5'-aminolevulinate synthase 2 Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene trophinin Neighboring gene MAGE family member D2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012104255.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012104255.1 Reference Mleu.le_1.0

    Range
    173721..233282
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011991972.1 → XP_011847362.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A2K5ZWP9, A0A2K5ZWU0
    Related
    ENSMLEP00000032241.1, ENSMLET00000055818.1
    Conserved Domains (2) summary
    pfam01591
    Location:7 → 186
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:189 → 375
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  2. XM_011991970.1 → XP_011847360.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

    See identical proteins and their annotated locations for XP_011847360.1

    UniProtKB/TrEMBL
    A0A2K5ZWR7
    Related
    ENSMLEP00000032248.1, ENSMLET00000055825.1
    Conserved Domains (2) summary
    pfam01591
    Location:41 → 259
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:262 → 445
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  3. XM_011991971.1 → XP_011847361.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

    See identical proteins and their annotated locations for XP_011847361.1

    UniProtKB/TrEMBL
    A0A2K5ZWR7
    Conserved Domains (2) summary
    pfam00300
    Location:240 → 426
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:38 → 237
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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