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OGDHL oxoglutarate dehydrogenase L [ Mandrillus leucophaeus (drill) ]

Gene ID: 105547381, updated on 13-Mar-2024

Summary

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Gene symbol
OGDHL
Gene description
oxoglutarate dehydrogenase L
See related
Ensembl:ENSMLEG00000038083
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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See OGDHL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012104120.1 (3087207..3121830, complement)

NW_012104120.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 18 member A3 Neighboring gene choline O-acetyltransferase Neighboring gene chromosome unknown open reading frame, human C10orf53 Neighboring gene mitogen-activated protein kinase 6-like Neighboring gene poly(ADP-ribose) glycohydrolase Neighboring gene translocase of inner mitochondrial membrane 23 homolog B

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012104120.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxoglutarate dehydrogenase (succinyl-transferring) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables thiamine pyrophosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of oxoglutarate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
2-oxoglutarate dehydrogenase-like, mitochondrial
Names
oxoglutarate dehydrogenase like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012104120.1 Reference Mleu.le_1.0

    Range
    3087207..3121830 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011990963.1 → XP_011846353.1  2-oxoglutarate dehydrogenase-like, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A2K5ZIY7
    Related
    ENSMLEP00000027776.1, ENSMLET00000051327.1
    Conserved Domains (5) summary
    PRK09404
    Location:73 → 1028
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed
    cd02016
    Location:278 → 541
    TPP_E1_OGDC_like; Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of ...
    pfam02779
    Location:663 → 877
    Transket_pyr; Transketolase, pyrimidine binding domain
    pfam16078
    Location:72 → 103
    2-oxogl_dehyd_N; 2-oxoglutarate dehydrogenase N-terminus
    pfam16870
    Location:884 → 1027
    OxoGdeHyase_C; 2-oxoglutarate dehydrogenase C-terminal

  2. XM_011990965.1 → XP_011846355.1  2-oxoglutarate dehydrogenase-like, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A2K5ZIY7, A0A2K5ZJ47
    Related
    ENSMLEP00000027780.1, ENSMLET00000051331.1
    Conserved Domains (5) summary
    PRK09404
    Location:46 → 944
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed
    cd02016
    Location:194 → 457
    TPP_E1_OGDC_like; Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of ...
    pfam02779
    Location:579 → 793
    Transket_pyr; Transketolase, pyrimidine binding domain
    pfam16078
    Location:45 → 68
    2-oxogl_dehyd_N; 2-oxoglutarate dehydrogenase N-terminus
    pfam16870
    Location:800 → 943
    OxoGdeHyase_C; 2-oxoglutarate dehydrogenase C-terminal

  3. XM_011990964.1 → XP_011846354.1  2-oxoglutarate dehydrogenase-like, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A2K5ZIY7
    Conserved Domains (5) summary
    PRK09404
    Location:60 → 1015
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed
    cd02016
    Location:265 → 528
    TPP_E1_OGDC_like; Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of ...
    pfam02779
    Location:650 → 864
    Transket_pyr; Transketolase, pyrimidine binding domain
    pfam16078
    Location:59 → 90
    2-oxogl_dehyd_N; 2-oxoglutarate dehydrogenase N-terminus
    pfam16870
    Location:871 → 1014
    OxoGdeHyase_C; 2-oxoglutarate dehydrogenase C-terminal

  4. XM_011990962.1 → XP_011846352.1  2-oxoglutarate dehydrogenase-like, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A2K5ZIY7
    Conserved Domains (5) summary
    PRK09404
    Location:73 → 1029
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed
    cd02016
    Location:278 → 541
    TPP_E1_OGDC_like; Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of ...
    pfam02779
    Location:663 → 878
    Transket_pyr; Transketolase, pyrimidine binding domain
    pfam16078
    Location:72 → 103
    2-oxogl_dehyd_N; 2-oxoglutarate dehydrogenase N-terminus
    pfam16870
    Location:885 → 1028
    OxoGdeHyase_C; 2-oxoglutarate dehydrogenase C-terminal
Nucleotide Protein
Heading Accession and Version

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