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PLCG2 phospholipase C gamma 2 [ Mandrillus leucophaeus (drill) ]

Gene ID: 105546817, updated on 13-Mar-2024

Summary

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Gene symbol
PLCG2
Gene description
phospholipase C gamma 2
See related
Ensembl:ENSMLEG00000036172
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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See PLCG2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
31
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012103920.1 (1261219..1472329, complement)

NW_012103920.1Genomic Context describing neighboring genes Neighboring gene hydroxysteroid 17-beta dehydrogenase 2 Neighboring gene short chain dehydrogenase/reductase family 42E, member 1 Neighboring gene c-Maf inducing protein Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012103920.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epithelial cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012103920.1 Reference Mleu.le_1.0

    Range
    1261219..1472329 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011990117.1 → XP_011845507.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

    UniProtKB/TrEMBL
    A0A2K5Z8B9, A0A2K5Z8J9
    Related
    ENSMLEP00000024056.1, ENSMLET00000047577.1
    Conserved Domains (9) summary
    cd00275
    Location:994 → 1120
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:311 → 458
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:579 → 677
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd11969
    Location:706 → 760
    SH3_PLCgamma2; Src homology 3 domain of Phospholipase C (PLC) gamma 2
    cd13234
    Location:773 → 843
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:22 → 140
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cl14615
    Location:859 → 964
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    cl15255
    Location:527 → 658
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:475 → 510
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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