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TRAF2 TNF receptor associated factor 2 [ Mandrillus leucophaeus (drill) ]

Gene ID: 105543266, updated on 13-Mar-2024

Summary

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Gene symbol
TRAF2
Gene description
TNF receptor associated factor 2
See related
Ensembl:ENSMLEG00000042841
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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See TRAF2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012102920.1 (2309461..2355993)

NW_012102920.1Genomic Context describing neighboring genes Neighboring gene MAM domain containing 4 Neighboring gene endothelial differentiation related factor 1 Neighboring gene F-box/WD repeat-containing protein 5-like Neighboring gene F-box and WD repeat domain containing 5 Neighboring gene complement C8 gamma chain

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012102920.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of NF-kappaB-inducing kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autoubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012102920.1 Reference Mleu.le_1.0

    Range
    2309461..2355993
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011985101.1 → XP_011840491.1  TNF receptor-associated factor 2

    See identical proteins and their annotated locations for XP_011840491.1

    UniProtKB/TrEMBL
    A0A2K6ABS1
    Related
    ENSMLEP00000037495.1, ENSMLET00000061104.1
    Conserved Domains (5) summary
    cd03778
    Location:334 → 497
    MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...
    TIGR00599
    Location:28 → 157
    rad18; DNA repair protein rad18
    pfam02176
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    pfam16673
    Location:269 → 329
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  2. XM_011985102.1 → XP_011840492.1  TNF receptor-associated factor 2

    See identical proteins and their annotated locations for XP_011840492.1

    UniProtKB/TrEMBL
    A0A2K6ABS1
    Conserved Domains (5) summary
    cd03778
    Location:334 → 497
    MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...
    TIGR00599
    Location:28 → 157
    rad18; DNA repair protein rad18
    pfam02176
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    pfam16673
    Location:269 → 329
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
Nucleotide Protein
Heading Accession and Version

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