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SPHK2 sphingosine kinase 2 [ Mandrillus leucophaeus (drill) ]

Gene ID: 105539178, updated on 13-Mar-2024

Summary

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Gene symbol
SPHK2
Gene description
sphingosine kinase 2
See related
Ensembl:ENSMLEG00000040417
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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See SPHK2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012102033.1 (1061171..1072146, complement)

NW_012102033.1Genomic Context describing neighboring genes Neighboring gene galactoside 2-alpha-L-fucosyltransferase 2-like Neighboring gene carbonic anhydrase 11 Neighboring gene D-box binding PAR bZIP transcription factor Neighboring gene ribosomal protein L18 Neighboring gene family with sequence similarity 83 member E Neighboring gene sperm acrosome associated 4 Neighboring gene sulfotransferase family 2B member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012102033.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables D-erythro-sphingosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphinganine-1-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingosine kinase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012102033.1 Reference Mleu.le_1.0

    Range
    1061171..1072146 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011979357.1 → XP_011834747.1  sphingosine kinase 2 isoform X1

    See identical proteins and their annotated locations for XP_011834747.1

    UniProtKB/TrEMBL
    A0A2K5ZXA4, A0A2K5ZXB6
    Related
    ENSMLEP00000032434.1, ENSMLET00000056011.1
    Conserved Domains (2) summary
    pfam00781
    Location:186 → 320
    DAGK_cat; Diacylglycerol kinase catalytic domain
    pfam06484
    Location:376 → 506
    Ten_N; Teneurin Intracellular Region

  2. XM_011979361.1 → XP_011834751.1  sphingosine kinase 2 isoform X4

    Conserved Domains (2) summary
    pfam00781
    Location:1 → 115
    DAGK_cat; Diacylglycerol kinase catalytic domain
    pfam06484
    Location:171 → 301
    Ten_N; Teneurin Intracellular Region

  3. XM_011979360.1 → XP_011834750.1  sphingosine kinase 2 isoform X3

    UniProtKB/TrEMBL
    A0A2K5ZXA4
    Conserved Domains (2) summary
    pfam00781
    Location:127 → 261
    DAGK_cat; Diacylglycerol kinase catalytic domain
    pfam06484
    Location:317 → 447
    Ten_N; Teneurin Intracellular Region

  4. XM_011979358.1 → XP_011834748.1  sphingosine kinase 2 isoform X1

    See identical proteins and their annotated locations for XP_011834748.1

    UniProtKB/TrEMBL
    A0A2K5ZXA4, A0A2K5ZXB6
    Conserved Domains (2) summary
    pfam00781
    Location:186 → 320
    DAGK_cat; Diacylglycerol kinase catalytic domain
    pfam06484
    Location:376 → 506
    Ten_N; Teneurin Intracellular Region

  5. XM_011979359.1 → XP_011834749.1  sphingosine kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A2K5ZXA4
    Related
    ENSMLEP00000032445.1, ENSMLET00000056022.1
    Conserved Domains (2) summary
    pfam00781
    Location:151 → 285
    DAGK_cat; Diacylglycerol kinase catalytic domain
    pfam06484
    Location:341 → 471
    Ten_N; Teneurin Intracellular Region
Nucleotide Protein
Heading Accession and Version

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