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PKM pyruvate kinase M1/2 [ Mandrillus leucophaeus (drill) ]

Gene ID: 105538680, updated on 13-Mar-2024

Summary

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Gene symbol
PKM
Gene description
pyruvate kinase M1/2
See related
Ensembl:ENSMLEG00000041947
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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See PKM in Genome Data Viewer
Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012101998.1 (3236483..3277658, complement)

NW_012101998.1Genomic Context describing neighboring genes Neighboring gene SUMO peptidase family member, NEDD8 specific Neighboring gene GRAM domain containing 2A Neighboring gene poly(ADP-ribose) polymerase family member 6 Neighboring gene CUGBP Elav-like family member 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012101998.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyruvate kinase PKM
Names
pyruvate kinase, muscle

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012101998.1 Reference Mleu.le_1.0

    Range
    3236483..3277658 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011978598.1 → XP_011833988.1  pyruvate kinase PKM isoform X5

    UniProtKB/TrEMBL
    A0A2K6A6I4, A0A2K6A6L0
    Related
    ENSMLEP00000035675.1, ENSMLET00000059274.1
    Conserved Domains (1) summary
    cd00288
    Location:42 → 456
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  2. XM_011978591.1 → XP_011833981.1  pyruvate kinase PKM isoform X2

    See identical proteins and their annotated locations for XP_011833981.1

    UniProtKB/TrEMBL
    A0A2K6A6K3, A0A2K6A6L0
    Related
    ENSMLEP00000035682.1, ENSMLET00000059281.1
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  3. XM_011978592.1 → XP_011833982.1  pyruvate kinase PKM isoform X3

    See identical proteins and their annotated locations for XP_011833982.1

    UniProtKB/TrEMBL
    A0A2K6A6J2, A0A2K6A6L0
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  4. XM_011978596.1 → XP_011833986.1  pyruvate kinase PKM isoform X4

    UniProtKB/TrEMBL
    A0A2K6A6G8, A0A2K6A6L0
    Related
    ENSMLEP00000035656.1, ENSMLET00000059255.1
    Conserved Domains (2) summary
    cd00288
    Location:68 → 515
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
    TIGR01064
    Location:68 → 512
    pyruv_kin; pyruvate kinase

  5. XM_011978594.1 → XP_011833984.1  pyruvate kinase PKM isoform X3

    See identical proteins and their annotated locations for XP_011833984.1

    UniProtKB/TrEMBL
    A0A2K6A6J2, A0A2K6A6L0
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  6. XM_011978595.1 → XP_011833985.1  pyruvate kinase PKM isoform X3

    See identical proteins and their annotated locations for XP_011833985.1

    UniProtKB/TrEMBL
    A0A2K6A6J2, A0A2K6A6L0
    Related
    ENSMLEP00000035681.1, ENSMLET00000059280.1
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  7. XM_011978593.1 → XP_011833983.1  pyruvate kinase PKM isoform X3

    See identical proteins and their annotated locations for XP_011833983.1

    UniProtKB/TrEMBL
    A0A2K6A6J2, A0A2K6A6L0
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  8. XM_011978590.1 → XP_011833980.1  pyruvate kinase PKM isoform X1

    UniProtKB/TrEMBL
    A0A2K6A6L0
    Conserved Domains (2) summary
    cd00288
    Location:102 → 590
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
    TIGR01064
    Location:103 → 587
    pyruv_kin; pyruvate kinase
Nucleotide Protein
Heading Accession and Version

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