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TPH2 tryptophan hydroxylase 2 [ Mandrillus leucophaeus (drill) ]

Gene ID: 105538610, updated on 13-Mar-2024

Summary

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Gene symbol
TPH2
Gene description
tryptophan hydroxylase 2
See related
Ensembl:ENSMLEG00000000709
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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See TPH2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012101987.1 (97351..197136, complement)

NW_012101987.1Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 15 Neighboring gene magnesium transporter MRS2 homolog, mitochondrial pseudogene Neighboring gene RAB21, member RAS oncogene family

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012101987.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tryptophan 5-monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in aromatic amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in serotonin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tryptophan 5-hydroxylase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012101987.1 Reference Mleu.le_1.0

    Range
    97351..197136 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011978503.1 → XP_011833893.1  tryptophan 5-hydroxylase 2

    See identical proteins and their annotated locations for XP_011833893.1

    UniProtKB/TrEMBL
    A0A2K5XAH0
    Related
    ENSMLEP00000000317.1, ENSMLET00000000828.1
    Conserved Domains (2) summary
    pfam00351
    Location:152 → 482
    Biopterin_H; Biopterin-dependent aromatic amino acid hydroxylase
    cl09141
    Location:64 → 137
    ACT; ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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