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PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial [ Mandrillus leucophaeus (drill) ]

Gene ID: 105532712, updated on 13-Mar-2024

Summary

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Gene symbol
PCK2
Gene description
phosphoenolpyruvate carboxykinase 2, mitochondrial
See related
Ensembl:ENSMLEG00000042569
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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See PCK2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012110697.1 (44464..54475)

NW_012110697.1Genomic Context describing neighboring genes Neighboring gene capping protein regulator and myosin 1 linker 3 Neighboring gene copine 6 Neighboring gene neural retina leucine zipper Neighboring gene DDB1 and CUL4 associated factor 11 Neighboring gene fat storage inducing transmembrane protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012110697.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoenolpyruvate carboxykinase (GTP) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to dexamethasone stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycerol biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hepatocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in propionate catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphoenolpyruvate carboxykinase [GTP], mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012110697.1 Reference Mleu.le_1.0

    Range
    44464..54475
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011970948.1 → XP_011826338.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X2

    Conserved Domains (1) summary
    cd00819
    Location:1 → 499
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...

  2. XM_011970947.1 → XP_011826337.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A2K6AA18, A0A2K6AA53
    Related
    ENSMLEP00000036924.1, ENSMLET00000060530.1
    Conserved Domains (1) summary
    cd00819
    Location:44 → 633
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...

  3. XM_011970949.1 → XP_011826339.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A2K6AA47
    Related
    ENSMLEP00000036922.1, ENSMLET00000060528.1
    Conserved Domains (1) summary
    cd00819
    Location:44 → 490
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...
Nucleotide Protein
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