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HAGH hydroxyacylglutathione hydrolase [ Mandrillus leucophaeus (drill) ]

Gene ID: 105529736, updated on 13-Mar-2024

Summary

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Gene symbol
HAGH
Gene description
hydroxyacylglutathione hydrolase
See related
Ensembl:ENSMLEG00000042252
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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See HAGH in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012108474.1 (2070378..2083805, complement)

NW_012108474.1Genomic Context describing neighboring genes Neighboring gene NUBP iron-sulfur cluster assembly factor 2, cytosolic Neighboring gene insulin like growth factor binding protein acid labile subunit Neighboring gene fumarylacetoacetate hydrolase domain containing 1 Neighboring gene uncharacterized LOC105529737

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012108474.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxyacylglutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxyacylglutathione hydrolase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012108474.1 Reference Mleu.le_1.0

    Range
    2070378..2083805 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011966950.1 → XP_011822340.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011822340.1

    UniProtKB/TrEMBL
    A0A2K6A889
    Conserved Domains (1) summary
    PLN02469
    Location:1 → 256
    PLN02469; hydroxyacylglutathione hydrolase

  2. XM_011966951.1 → XP_011822341.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011822341.1

    UniProtKB/TrEMBL
    A0A2K6A889
    Related
    ENSMLEP00000036257.1, ENSMLET00000059857.1
    Conserved Domains (1) summary
    PLN02469
    Location:1 → 256
    PLN02469; hydroxyacylglutathione hydrolase

  3. XM_011966952.1 → XP_011822342.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A2K6A897
    Related
    ENSMLEP00000036258.1, ENSMLET00000059858.1
    Conserved Domains (3) summary
    COG0491
    Location:8 → 228
    GloB; Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II [General function prediction only]
    pfam16123
    Location:174 → 228
    HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
    cd07723
    Location:4 → 173
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

RNA

  1. XR_001004557.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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