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HAGH hydroxyacylglutathione hydrolase [ Colobus angolensis palliatus ]

Gene ID: 105522861, updated on 13-Mar-2024

Summary

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Gene symbol
HAGH
Gene description
hydroxyacylglutathione hydrolase
See related
Ensembl:ENSCANG00000033668
Gene type
protein coding
RefSeq status
MODEL
Organism
Colobus angolensis palliatus (sub-species: palliatus)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Colobus
Orthologs
human mouse all
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Genomic context

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See HAGH in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current Cang.pa_1.0 (GCF_000951035.1) Unplaced Scaffold NW_012117855.1 (62981..93565)

NW_012117855.1Genomic Context describing neighboring genes Neighboring gene meiosis specific with OB-fold Neighboring gene fumarylacetoacetate hydrolase domain containing 1 Neighboring gene insulin like growth factor binding protein acid labile subunit Neighboring gene NUBP iron-sulfur cluster assembly factor 2, cytosolic

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012117855.1 Unplaced Scaffold Reference Cang.pa_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxyacylglutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxyacylglutathione hydrolase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Colobus angolensis palliatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cang.pa_1.0

Genomic

  1. NW_012117855.1 Reference Cang.pa_1.0

    Range
    62981..93565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011957458.1 → XP_011812848.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_011812848.1

    UniProtKB/TrEMBL
    A0A2K5IUZ5
    Related
    ENSCANP00000020493.1, ENSCANT00000043465.1
    Conserved Domains (3) summary
    PLN02469
    Location:1 → 256
    PLN02469; hydroxyacylglutathione hydrolase
    pfam16123
    Location:174 → 253
    HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
    cd07723
    Location:4 → 173
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

  2. XM_011957455.1 → XP_011812845.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_011812845.1

    UniProtKB/TrEMBL
    A0A2K5IUZ5
    Conserved Domains (3) summary
    PLN02469
    Location:1 → 256
    PLN02469; hydroxyacylglutathione hydrolase
    pfam16123
    Location:174 → 253
    HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
    cd07723
    Location:4 → 173
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

  3. XM_011957454.1 → XP_011812844.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A2K5IVA1
    Related
    ENSCANP00000020510.1, ENSCANT00000043482.1
    Conserved Domains (3) summary
    COG0491
    Location:8 → 226
    GloB; Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II [General function prediction only]
    pfam16123
    Location:174 → 228
    HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
    cd07723
    Location:4 → 173
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

  4. XM_011957457.1 → XP_011812847.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A2K5IVJ3
    Related
    ENSCANP00000020506.1, ENSCANT00000043478.1
    Conserved Domains (1) summary
    cd07723
    Location:4 → 100
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain
Nucleotide Protein
Heading Accession and Version

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