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PLEC plectin [ Colobus angolensis palliatus ]

Gene ID: 105509105, updated on 13-Mar-2024

Summary

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Gene symbol
PLEC
Gene description
plectin
See related
Ensembl:ENSCANG00000037340
Gene type
protein coding
RefSeq status
MODEL
Organism
Colobus angolensis palliatus (sub-species: palliatus)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Colobus
Orthologs
human mouse all
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Genomic context

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See PLEC in Genome Data Viewer
Location:
chromosome: Un
Exon count:
31
Annotation release Status Assembly Chr Location
100 current Cang.pa_1.0 (GCF_000951035.1) Unplaced Scaffold NW_012114821.1 (1215433..1242090)

NW_012114821.1Genomic Context describing neighboring genes Neighboring gene glutamate ionotropic receptor NMDA type subunit associated protein 1 Neighboring gene poly(ADP-ribose) polymerase family member 10 Neighboring gene epiplakin 1 Neighboring gene nuclear receptor binding protein 2 Neighboring gene poly(U) binding splicing factor 60

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012114821.1 Unplaced Scaffold Reference Cang.pa_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables keratin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intermediate filament bundle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in wound healing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in keratin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plectin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Colobus angolensis palliatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cang.pa_1.0

Genomic

  1. NW_012114821.1 Reference Cang.pa_1.0

    Range
    1215433..1242090
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011938213.1 → XP_011793603.1  plectin

    UniProtKB/TrEMBL
    A0A2K5JJ88
    Related
    ENSCANP00000028892.1, ENSCANT00000051993.1
    Conserved Domains (10) summary
    smart00250
    Location:2636 → 2672
    PLEC; Plectin repeat
    cd00014
    Location:47 → 149
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:560 → 749
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:164 → 262
    CH; Calponin homology (CH) domain
    pfam00681
    Location:3582 → 3623
    Plectin; Plectin repeat
    pfam13868
    Location:1805 → 2151
    TPH; Trichohyalin-plectin-homology domain
    pfam15665
    Location:1361 → 1589
    FAM184; Family with sequence similarity 184, A and B
    cd16269
    Location:1385 → 1396
    GBP_C; coiled coil [structural motif]
    cl12013
    Location:1814 → 2017
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    cl20817
    Location:1294 → 1421
    GBP_C; Guanylate-binding protein, C-terminal domain
Nucleotide Protein
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