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LTA4H leukotriene A4 hydrolase [ Colobus angolensis palliatus ]

Gene ID: 105506191, updated on 13-Mar-2024

Summary

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Gene symbol
LTA4H
Gene description
leukotriene A4 hydrolase
See related
Ensembl:ENSCANG00000031015
Gene type
protein coding
RefSeq status
MODEL
Organism
Colobus angolensis palliatus (sub-species: palliatus)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Colobus
Orthologs
human mouse all
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Genomic context

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See LTA4H in Genome Data Viewer
Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
100 current Cang.pa_1.0 (GCF_000951035.1) Unplaced Scaffold NW_012110919.1 (7153433..7195944, complement)

NW_012110919.1Genomic Context describing neighboring genes Neighboring gene amidohydrolase domain containing 1 Neighboring gene histidine ammonia-lyase Neighboring gene ETS transcription factor ELK3 Neighboring gene cyclin dependent kinase 17 Neighboring gene small nuclear ribonucleoprotein Sm D1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012110919.1 Unplaced Scaffold Reference Cang.pa_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aminopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables epoxide hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables leukotriene-A4 hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in leukotriene biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leukotriene A-4 hydrolase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Colobus angolensis palliatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cang.pa_1.0

Genomic

  1. NW_012110919.1 Reference Cang.pa_1.0

    Range
    7153433..7195944 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011934251.1 → XP_011789641.1  leukotriene A-4 hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A2K5IF19, A0A2K5IF29
    Related
    ENSCANP00000015156.1, ENSCANT00000038089.1
    Conserved Domains (3) summary
    cd09599
    Location:30 → 426
    M1_LTA4H; Peptidase M1 family contains leukotriene A4 hydrolase
    TIGR02411
    Location:30 → 584
    leuko_A4_hydro; leukotriene A-4 hydrolase/aminopeptidase
    pfam09127
    Location:444 → 583
    Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal

  2. XM_011934241.1 → XP_011789631.1  leukotriene A-4 hydrolase isoform X1

    UniProtKB/TrEMBL
    A0A2K5IEQ9
    Related
    ENSCANP00000015163.1, ENSCANT00000038096.1
    Conserved Domains (1) summary
    TIGR02411
    Location:6 → 608
    leuko_A4_hydro; leukotriene A-4 hydrolase/aminopeptidase
Nucleotide Protein
Heading Accession and Version

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