U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PKLR pyruvate kinase L/R [ Macaca nemestrina (pig-tailed macaque) ]

Gene ID: 105498012, updated on 13-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
PKLR
Gene description
pyruvate kinase L/R
See related
Ensembl:ENSMNEG00000009109
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca nemestrina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PKLR in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012012022.1 (6000691..6012315, complement)

NW_012012022.1Genomic Context describing neighboring genes Neighboring gene secretory carrier membrane protein 3 Neighboring gene CDC like kinase 2 Neighboring gene hyperpolarization activated cyclic nucleotide gated potassium channel 3 Neighboring gene farnesyl diphosphate synthase Neighboring gene putative uncharacterized protein RUSC1-AS1 Neighboring gene RUN and SH3 domain containing 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_012012022 Unplaced Scaffold Reference Mnem_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
pyruvate kinase PKLR
Names
pyruvate kinase, liver and RBC

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnem_1.0

Genomic

  1. NW_012012022.1 Reference Mnem_1.0

    Range
    6000691..6012315 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011769734.1 → XP_011768036.1  pyruvate kinase PKLR isoform X1

    UniProtKB/TrEMBL
    A0A2K6AS83
    Conserved Domains (2) summary
    cd00288
    Location:85 → 573
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
    TIGR01064
    Location:86 → 570
    pyruv_kin; pyruvate kinase

  2. XM_011769735.2 → XP_011768037.1  pyruvate kinase PKLR isoform X2

    See identical proteins and their annotated locations for XP_011768037.1

    UniProtKB/TrEMBL
    A0A2K6AS83, A0A2K6AS89
    Related
    ENSMNEP00000002011.1, ENSMNET00000009932.1
    Conserved Domains (2) summary
    cd00288
    Location:77 → 565
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
    TIGR01064
    Location:78 → 562
    pyruv_kin; pyruvate kinase

  3. XM_011769736.2 → XP_011768038.1  pyruvate kinase PKLR isoform X3

    UniProtKB/TrEMBL
    A0A2K6AS83
    Conserved Domains (2) summary
    cd00288
    Location:115 → 603
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
    TIGR01064
    Location:116 → 600
    pyruv_kin; pyruvate kinase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.