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SHMT1 serine hydroxymethyltransferase 1 [ Macaca nemestrina (pig-tailed macaque) ]

Gene ID: 105491103, updated on 13-Mar-2024

Summary

Gene symbol
SHMT1
Gene description
serine hydroxymethyltransferase 1
See related
Ensembl:ENSMNEG00000044262
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca nemestrina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Annotation information
Annotation category: partial on reference assembly
Orthologs
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Genomic context

See SHMT1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012011333.1 (223093..258107)

NW_012011333.1Genomic Context describing neighboring genes Neighboring gene coactosin-like protein pseudogene Neighboring gene TBC1 domain family member 3G-like Neighboring gene SMCR8-C9orf72 complex subunit Neighboring gene DNA topoisomerase III alpha

Genomic regions, transcripts, and products

Genomic Sequence:
NW_012011333 Unplaced Scaffold Reference Mnem_1.0

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cobalt ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables glycine hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables mRNA 5'-UTR binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables mRNA regulatory element binding translation repressor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables serine binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in L-serine catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to leukemia inhibitory factor IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in folic acid metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein homotetramerization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in purine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
serine hydroxymethyltransferase, cytosolic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnem_1.0

Genomic

  1. NW_012011333.1 Reference Mnem_1.0

    Range
    223093..258107
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011757265.2XP_011755567.2  serine hydroxymethyltransferase, cytosolic

    UniProtKB/TrEMBL
    A0A2K6E4R2
    Related
    ENSMNEP00000043134.1, ENSMNET00000067639.1
    Conserved Domains (1) summary
    PLN03226
    Location:20468
    PLN03226; serine hydroxymethyltransferase; Provisional