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GUF1 GTP binding elongation factor GUF1 [ Macaca nemestrina (pig-tailed macaque) ]

Gene ID: 105487693, updated on 13-Mar-2024

Summary

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Gene symbol
GUF1
Gene description
GTP binding elongation factor GUF1
See related
Ensembl:ENSMNEG00000008365
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca nemestrina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See GUF1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012011022.1 (4008493..4029466, complement)

NW_012011022.1Genomic Context describing neighboring genes Neighboring gene 52 kDa repressor of the inhibitor of the protein kinase-like Neighboring gene uncharacterized LOC112427709 Neighboring gene glucosamine-6-phosphate deaminase 2 Neighboring gene Yip1 domain family member 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012011022 Unplaced Scaffold Reference Mnem_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mitochondrial ribosome binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
translation factor GUF1, mitochondrial
Names
GUF1 homolog, GTPase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnem_1.0

Genomic

  1. NW_012011022.1 Reference Mnem_1.0

    Range
    4008493..4029466 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011751236.2 → XP_011749538.1  translation factor GUF1, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A2K6ARR8
    Conserved Domains (6) summary
    PRK05433
    Location:58 → 632
    PRK05433; GTP-binding protein LepA; Provisional
    cd03709
    Location:438 → 517
    lepA_C; lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits ...
    pfam06421
    Location:525 → 631
    LepA_C; GTP-binding protein LepA C-terminus
    cd03699
    Location:221 → 306
    EF4_II; Domain II of Elongation Factor 4 (EF4)
    cd16260
    Location:322 → 397
    EF4_III; Domain III of Elongation Factor 4 (EF4)
    cl21455
    Location:63 → 213
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_011751235.2 → XP_011749537.1  translation factor GUF1, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A2K6ARR8
    Conserved Domains (6) summary
    PRK05433
    Location:58 → 633
    PRK05433; GTP-binding protein LepA; Provisional
    cd03709
    Location:439 → 518
    lepA_C; lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits ...
    pfam06421
    Location:526 → 632
    LepA_C; GTP-binding protein LepA C-terminus
    cd03699
    Location:222 → 307
    EF4_II; Domain II of Elongation Factor 4 (EF4)
    cd16260
    Location:323 → 398
    EF4_III; Domain III of Elongation Factor 4 (EF4)
    cl21455
    Location:63 → 214
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_011751238.2 → XP_011749540.1  translation factor GUF1, mitochondrial isoform X5

    UniProtKB/TrEMBL
    A0A2K6ARR8
    Conserved Domains (6) summary
    cd01890
    Location:63 → 240
    LepA; LepA also known as Elongation Factor 4 (EF4)
    PRK05433
    Location:58 → 587
    PRK05433; GTP-binding protein LepA; Provisional
    cd03709
    Location:393 → 472
    lepA_C; lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits ...
    pfam06421
    Location:480 → 586
    LepA_C; GTP-binding protein LepA C-terminus
    cl02787
    Location:248 → 304
    Translation_Factor_II_like; Domain II of Elongation factor Tu (EF-Tu)-like proteins
    cl20541
    Location:308 → 352
    EFG_III-like; Domain III of Elongation factor G (EF-G) and related proteins

  4. XM_011751237.2 → XP_011749539.1  translation factor GUF1, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A2K6ARR8
    Related
    ENSMNEP00000001850.1, ENSMNET00000009172.1
    Conserved Domains (6) summary
    cd01890
    Location:63 → 240
    LepA; LepA also known as Elongation Factor 4 (EF4)
    PRK05433
    Location:58 → 611
    PRK05433; GTP-binding protein LepA; Provisional
    cd03709
    Location:436 → 496
    lepA_C; lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits ...
    pfam06421
    Location:504 → 610
    LepA_C; GTP-binding protein LepA C-terminus
    cd03699
    Location:248 → 333
    EF4_II; Domain II of Elongation Factor 4 (EF4)
    cd16260
    Location:349 → 424
    EF4_III; Domain III of Elongation Factor 4 (EF4)

  5. XM_011751233.2 → XP_011749535.1  translation factor GUF1, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011749535.1

    UniProtKB/TrEMBL
    A0A2K6ARR8, A0A2K6ARS3
    Related
    ENSMNEP00000001846.1, ENSMNET00000009159.1
    Conserved Domains (6) summary
    cd01890
    Location:63 → 240
    LepA; LepA also known as Elongation Factor 4 (EF4)
    PRK05433
    Location:58 → 659
    PRK05433; GTP-binding protein LepA; Provisional
    cd03709
    Location:465 → 544
    lepA_C; lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits ...
    pfam06421
    Location:552 → 658
    LepA_C; GTP-binding protein LepA C-terminus
    cd03699
    Location:248 → 333
    EF4_II; Domain II of Elongation Factor 4 (EF4)
    cd16260
    Location:349 → 424
    EF4_III; Domain III of Elongation Factor 4 (EF4)

RNA

  1. XR_003019414.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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