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DBT dihydrolipoamide branched chain transacylase E2 [ Macaca nemestrina (pig-tailed macaque) ]

Gene ID: 105485459, updated on 13-Mar-2024

Summary

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Gene symbol
DBT
Gene description
dihydrolipoamide branched chain transacylase E2
See related
Ensembl:ENSMNEG00000044927
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca nemestrina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DBT in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012010845.1 (9316162..9408804, complement)

NW_012010845.1Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 14A Neighboring gene SAS-6 centriolar assembly protein Neighboring gene tRNA methyltransferase 13 homolog Neighboring gene leucine rich repeat containing 39 Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene keratinocyte-associated transmembrane protein 2 pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012010845 Unplaced Scaffold Reference Mnem_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipoic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnem_1.0

Genomic

  1. NW_012010845.1 Reference Mnem_1.0

    Range
    9316162..9408804 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011747825.2 → XP_011746127.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_011746127.1

    UniProtKB/TrEMBL
    A0A2K6E9A4, A0A2K6E9C5
    Related
    ENSMNEP00000044757.1, ENSMNET00000069268.1
    Conserved Domains (4) summary
    cd06849
    Location:65 → 138
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    PLN02528
    Location:67 → 482
    PLN02528; 2-oxoisovalerate dehydrogenase E2 component
    pfam00198
    Location:267 → 479
    2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
    pfam02817
    Location:172 → 205
    E3_binding; e3 binding domain

  2. XM_011747826.2 → XP_011746128.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_011746128.1

    UniProtKB/TrEMBL
    A0A2K6E9A4, A0A2K6E9C5
    Related
    ENSMNEP00000044754.1, ENSMNET00000069265.1
    Conserved Domains (4) summary
    cd06849
    Location:65 → 138
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    PLN02528
    Location:67 → 482
    PLN02528; 2-oxoisovalerate dehydrogenase E2 component
    pfam00198
    Location:267 → 479
    2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
    pfam02817
    Location:172 → 205
    E3_binding; e3 binding domain

  3. XM_011747824.1 → XP_011746126.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A2K6E9A4
    Conserved Domains (4) summary
    cd06849
    Location:111 → 184
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    PLN02528
    Location:113 → 528
    PLN02528; 2-oxoisovalerate dehydrogenase E2 component
    pfam00198
    Location:313 → 525
    2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
    pfam02817
    Location:218 → 251
    E3_binding; e3 binding domain
Nucleotide Protein
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