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CRACR2A calcium release activated channel regulator 2A [ Macaca nemestrina (pig-tailed macaque) ]

Gene ID: 105484140, updated on 13-Mar-2024

Summary

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Gene symbol
CRACR2A
Gene description
calcium release activated channel regulator 2A
See related
Ensembl:ENSMNEG00000031773
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca nemestrina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See CRACR2A in Genome Data Viewer
Location:
chromosome: Un
Exon count:
27
Annotation release Status Assembly Chr Location
101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012020298.1 (2967653..3105495, complement)

NW_012020298.1Genomic Context describing neighboring genes Neighboring gene 10 kDa heat shock protein, mitochondrial Neighboring gene uncharacterized LOC105484135 Neighboring gene protein arginine methyltransferase 8 Neighboring gene poly(ADP-ribose) polymerase family member 11 Neighboring gene uncharacterized LOC105484143

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012020298 Unplaced Scaffold Reference Mnem_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
EF-hand calcium-binding domain-containing protein 4B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnem_1.0

Genomic

  1. NW_012020298.1 Reference Mnem_1.0

    Range
    2967653..3105495 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011745470.2 → XP_011743772.1  EF-hand calcium-binding domain-containing protein 4B isoform X1

    See identical proteins and their annotated locations for XP_011743772.1

    UniProtKB/TrEMBL
    A0A2K6BV92
    Conserved Domains (5) summary
    smart00175
    Location:546 → 709
    RAB; Rab subfamily of small GTPases
    cd00154
    Location:546 → 704
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    pfam13499
    Location:55 → 109
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:54 → 114
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl23720
    Location:226 → 313
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  2. XM_011745469.2 → XP_011743771.1  EF-hand calcium-binding domain-containing protein 4B isoform X1

    See identical proteins and their annotated locations for XP_011743771.1

    UniProtKB/TrEMBL
    A0A2K6BV92
    Conserved Domains (5) summary
    smart00175
    Location:546 → 709
    RAB; Rab subfamily of small GTPases
    cd00154
    Location:546 → 704
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    pfam13499
    Location:55 → 109
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:54 → 114
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl23720
    Location:226 → 313
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  3. XM_011745468.2 → XP_011743770.1  EF-hand calcium-binding domain-containing protein 4B isoform X1

    See identical proteins and their annotated locations for XP_011743770.1

    UniProtKB/TrEMBL
    A0A2K6BV92
    Conserved Domains (5) summary
    smart00175
    Location:546 → 709
    RAB; Rab subfamily of small GTPases
    cd00154
    Location:546 → 704
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    pfam13499
    Location:55 → 109
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:54 → 114
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl23720
    Location:226 → 313
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  4. XM_011745471.2 → XP_011743773.1  EF-hand calcium-binding domain-containing protein 4B isoform X1

    See identical proteins and their annotated locations for XP_011743773.1

    UniProtKB/TrEMBL
    A0A2K6BV92
    Related
    ENSMNEP00000015315.1, ENSMNET00000039523.1
    Conserved Domains (5) summary
    smart00175
    Location:546 → 709
    RAB; Rab subfamily of small GTPases
    cd00154
    Location:546 → 704
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    pfam13499
    Location:55 → 109
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:54 → 114
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl23720
    Location:226 → 313
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  5. XM_011745477.2 → XP_011743779.1  EF-hand calcium-binding domain-containing protein 4B isoform X3

    Conserved Domains (4) summary
    smart00175
    Location:436 → 599
    RAB; Rab subfamily of small GTPases
    cd00154
    Location:436 → 594
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    pfam13499
    Location:55 → 109
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:54 → 114
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  6. XM_011745473.2 → XP_011743775.1  EF-hand calcium-binding domain-containing protein 4B isoform X1

    See identical proteins and their annotated locations for XP_011743775.1

    UniProtKB/TrEMBL
    A0A2K6BV92
    Conserved Domains (5) summary
    smart00175
    Location:546 → 709
    RAB; Rab subfamily of small GTPases
    cd00154
    Location:546 → 704
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    pfam13499
    Location:55 → 109
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:54 → 114
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl23720
    Location:226 → 313
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  7. XM_011745472.2 → XP_011743774.1  EF-hand calcium-binding domain-containing protein 4B isoform X1

    See identical proteins and their annotated locations for XP_011743774.1

    UniProtKB/TrEMBL
    A0A2K6BV92
    Conserved Domains (5) summary
    smart00175
    Location:546 → 709
    RAB; Rab subfamily of small GTPases
    cd00154
    Location:546 → 704
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    pfam13499
    Location:55 → 109
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:54 → 114
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl23720
    Location:226 → 313
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  8. XM_011745475.2 → XP_011743777.1  EF-hand calcium-binding domain-containing protein 4B isoform X1

    See identical proteins and their annotated locations for XP_011743777.1

    UniProtKB/TrEMBL
    A0A2K6BV92
    Related
    ENSMNEP00000015325.1, ENSMNET00000039533.1
    Conserved Domains (5) summary
    smart00175
    Location:546 → 709
    RAB; Rab subfamily of small GTPases
    cd00154
    Location:546 → 704
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    pfam13499
    Location:55 → 109
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:54 → 114
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl23720
    Location:226 → 313
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  9. XM_011745476.2 → XP_011743778.1  EF-hand calcium-binding domain-containing protein 4B isoform X2

    UniProtKB/TrEMBL
    A0A2K6BVA3
    Related
    ENSMNEP00000015329.1, ENSMNET00000039537.1
    Conserved Domains (4) summary
    cd00154
    Location:546 → 652
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    pfam13499
    Location:55 → 109
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:54 → 114
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl23720
    Location:226 → 313
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
Nucleotide Protein
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