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SFRP1 secreted frizzled related protein 1 [ Macaca nemestrina (pig-tailed macaque) ]

Gene ID: 105476541, updated on 13-Mar-2024

Summary

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Gene symbol
SFRP1
Gene description
secreted frizzled related protein 1
See related
Ensembl:ENSMNEG00000036962
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca nemestrina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See SFRP1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012016355.1 (3291023..3338756)

NW_012016355.1Genomic Context describing neighboring genes Neighboring gene golgin A7 Neighboring gene small nucleolar RNA SNORD65 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene zinc finger matrin-type 4 Neighboring gene 40S ribosomal protein S26-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012016355 Unplaced Scaffold Reference Mnem_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
secreted frizzled-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnem_1.0

Genomic

  1. NW_012016355.1 Reference Mnem_1.0

    Range
    3291023..3338756
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011732552.2 → XP_011730854.1  secreted frizzled-related protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011730854.1

    UniProtKB/TrEMBL
    A0A2K6CTV2, A0A2K6CTW4
    Related
    ENSMNEP00000027122.1, ENSMNET00000051412.1
    Conserved Domains (2) summary
    cd07443
    Location:52 → 175
    CRD_SFRP1; Cysteine-rich domain of the secreted frizzled-related protein 1 (SFRP1), a regulator of Wnt activity
    cd03580
    Location:183 → 306
    NTR_Sfrp1_like; NTR domain, Secreted frizzled-related protein (Sfrp) 1-like subfamily; composed of proteins similar to human Sfrp1, Sfrp2 and Sfrp5. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse ...

  2. XM_024791165.1 → XP_024646933.1  secreted frizzled-related protein 1 isoform X2

    Conserved Domains (2) summary
    cd07443
    Location:52 → 175
    CRD_SFRP1; Cysteine-rich domain of the secreted frizzled-related protein 1 (SFRP1), a regulator of Wnt activity
    cl02512
    Location:183 → 207
    NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...
Nucleotide Protein
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