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ALOX12B arachidonate 12-lipoxygenase, 12R type [ Macaca nemestrina (pig-tailed macaque) ]

Gene ID: 105473874, updated on 13-Mar-2024

Summary

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Gene symbol
ALOX12B
Gene description
arachidonate 12-lipoxygenase, 12R type
See related
Ensembl:ENSMNEG00000042459
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca nemestrina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See ALOX12B in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012010689.1 (8879097..8894064, complement)

NW_012010689.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene arachidonate 15-lipoxygenase type B Neighboring gene arachidonate epidermal lipoxygenase 3 Neighboring gene transfer RNA lysine (anticodon UUU)

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012010689 Unplaced Scaffold Reference Mnem_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 12(S)-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 12-lipoxygenase, 12R-type

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnem_1.0

Genomic

  1. NW_012010689.1 Reference Mnem_1.0

    Range
    8879097..8894064 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011728025.1 → XP_011726327.1  arachidonate 12-lipoxygenase, 12R-type

    UniProtKB/TrEMBL
    A0A2K6DST2
    Related
    ENSMNEP00000038973.1, ENSMNET00000063456.1
    Conserved Domains (2) summary
    cd01753
    Location:2 → 116
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:258 → 681
    Lipoxygenase; Lipoxygenase
Nucleotide Protein
Heading Accession and Version

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