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MASP1 MBL associated serine protease 1 [ Macaca nemestrina (pig-tailed macaque) ]

Gene ID: 105470889, updated on 13-Mar-2024

Summary

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Gene symbol
MASP1
Gene description
MBL associated serine protease 1
See related
Ensembl:ENSMNEG00000031506
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca nemestrina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MASP1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012014355.1 (10766524..10839645)

NW_012014355.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105470892 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC112424778 Neighboring gene receptor transporter protein 4 Neighboring gene receptor transporter protein 1 Neighboring gene ribosomal protein L39 like Neighboring gene ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Neighboring gene 60S ribosomal protein L29-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012014355 Unplaced Scaffold Reference Mnem_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 1
Names
mannan binding lectin serine peptidase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnem_1.0

Genomic

  1. NW_012014355.1 Reference Mnem_1.0

    Range
    10766524..10839645
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024789452.1 → XP_024645220.1  mannan-binding lectin serine protease 1 isoform X2

    UniProtKB/TrEMBL
    A0A2K6BTX2
    Conserved Domains (6) summary
    cd00033
    Location:270 → 332
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00020
    Location:418 → 680
    Tryp_SPc; Trypsin-like serine protease
    pfam00431
    Location:154 → 263
    CUB; CUB domain
    cl00049
    Location:50 → 106
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:336 → 401
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:122 → 150
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_011723173.2 → XP_011721475.1  mannan-binding lectin serine protease 1 isoform X1

    UniProtKB/TrEMBL
    A0A2K6BTS9
    Related
    ENSMNEP00000014821.1, ENSMNET00000039027.1
    Conserved Domains (6) summary
    cd00033
    Location:301 → 363
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02639
    Location:300 → 433
    PHA02639; EEV host range protein; Provisional
    cd00041
    Location:28 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:449 → 694
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_011723174.2 → XP_011721476.1  mannan-binding lectin serine protease 1 isoform X5

    See identical proteins and their annotated locations for XP_011721476.1

    UniProtKB/TrEMBL
    A0A2K6BTU7
    Related
    ENSMNEP00000014833.1, ENSMNET00000039040.1
    Conserved Domains (4) summary
    cd00033
    Location:301 → 363
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd00041
    Location:28 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  4. XM_024789454.1 → XP_024645222.1  mannan-binding lectin serine protease 1 isoform X4

    UniProtKB/TrEMBL
    A0A2K6BTX2
    Related
    ENSMNEP00000014827.1, ENSMNET00000039034.1
    Conserved Domains (6) summary
    cd00033
    Location:188 → 250
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02639
    Location:187 → 320
    PHA02639; EEV host range protein; Provisional
    smart00020
    Location:336 → 598
    Tryp_SPc; Trypsin-like serine protease
    pfam00431
    Location:72 → 181
    CUB; CUB domain
    pfam14670
    Location:40 → 68
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:8 → 67
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  5. XM_024789453.1 → XP_024645221.1  mannan-binding lectin serine protease 1 isoform X3

    UniProtKB/TrEMBL
    A0A2K6BTX2
    Conserved Domains (5) summary
    smart00020
    Location:379 → 641
    Tryp_SPc; Trypsin-like serine protease
    pfam00431
    Location:115 → 224
    CUB; CUB domain
    cl00049
    Location:11 → 67
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:231 → 292
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:83 → 111
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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