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PARN poly(A)-specific ribonuclease [ Macaca nemestrina (pig-tailed macaque) ]

Gene ID: 105467735, updated on 13-Mar-2024

Summary

Gene symbol
PARN
Gene description
poly(A)-specific ribonuclease
See related
Ensembl:ENSMNEG00000045108
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca nemestrina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See PARN in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012013466.1 (1701326..1914171)

NW_012013466.1Genomic Context describing neighboring genes Neighboring gene phospholipase A2 group X Neighboring gene U7 small nuclear RNA Neighboring gene bifunctional apoptosis regulator Neighboring gene uncharacterized LOC112424270 Neighboring gene uncharacterized LOC105467915 Neighboring gene uncharacterized LOC105467736

Genomic regions, transcripts, and products

Genomic Sequence:
NW_012013466 Unplaced Scaffold Reference Mnem_1.0

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables poly(A)-specific ribonuclease activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA poly(A) tail shortening IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
poly(A)-specific ribonuclease PARN

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnem_1.0

Genomic

  1. NW_012013466.1 Reference Mnem_1.0

    Range
    1701326..1914171
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011717416.1XP_011715718.1  poly(A)-specific ribonuclease PARN isoform X1

    UniProtKB/TrEMBL
    A0A2K6EAH7, A0A2K6EAJ3
    Related
    ENSMNEP00000045160.1, ENSMNET00000069671.1
    Conserved Domains (3) summary
    cd02637
    Location:181246
    R3H_PARN; R3H domain of Poly(A)-specific ribonuclease (PARN). PARN is a poly(A)-specific 3' exonuclease from the RNase D family that, in Xenopus, deadenylates a specific class of maternal mRNAs which results in their translational repression. The name of the R3H ...
    pfam04857
    Location:5390
    CAF1; CAF1 family ribonuclease
    pfam08675
    Location:438512
    RNA_bind; RNA binding domain
  2. XM_011717420.1XP_011715722.1  poly(A)-specific ribonuclease PARN isoform X3

    UniProtKB/TrEMBL
    A0A2K6EAJ3
    Conserved Domains (2) summary
    pfam04857
    Location:3364
    CAF1; CAF1 family ribonuclease
    pfam08675
    Location:412486
    RNA_bind; RNA binding domain
  3. XM_011717419.2XP_011715721.1  poly(A)-specific ribonuclease PARN isoform X2

    UniProtKB/TrEMBL
    A0A2K6EAJ3
    Conserved Domains (3) summary
    cd02637
    Location:166231
    R3H_PARN; R3H domain of Poly(A)-specific ribonuclease (PARN). PARN is a poly(A)-specific 3' exonuclease from the RNase D family that, in Xenopus, deadenylates a specific class of maternal mRNAs which results in their translational repression. The name of the R3H ...
    pfam04857
    Location:221375
    CAF1; CAF1 family ribonuclease
    pfam08675
    Location:423497
    RNA_bind; RNA binding domain