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SCPPPQ1 secretory calcium-binding phosphoprotein proline-glutamine rich 1 [ Homo sapiens (human) ]

Gene ID: 105377321, updated on 13-Mar-2024

Summary

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Official Symbol
SCPPPQ1provided by HGNC
Official Full Name
secretory calcium-binding phosphoprotein proline-glutamine rich 1provided by HGNC
Primary source
HGNC:HGNC:56851
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

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Location:
4q22.1
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (87460802..87471050, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (90789843..90800066, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L19 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21707 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:88343613-88344547 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:88345091-88345594 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:88345595-88346096 Neighboring gene nudix hydrolase 9 Neighboring gene SPARC like 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:88432037-88432537 Neighboring gene uncharacterized LOC124900729 Neighboring gene NANOG hESC enhancer GRCh37_chr4:88441567-88442068 Neighboring gene dentin sialophosphoprotein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Characterisation of secretory calcium-binding phosphoprotein-proline-glutamine-rich 1: a novel basal lamina component expressed at cell-tooth interfaces. Moffatt P, et al. Cell Tissue Res, 2014 Dec. PMID 25193156
  2. The SCPP gene repertoire in bony vertebrates and graded differences in mineralized tissues. Kawasaki K. Dev Genes Evol, 2009 Mar. PMID 19255778, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

Genotypes

General gene information

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Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
secretory calcium-binding phosphoprotein proline-glutamine rich 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001405228.1 → NP_001392157.1  secretory calcium-binding phosphoprotein proline-glutamine rich 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC112250
    UniProtKB/Swiss-Prot
    A0A411D538

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    87460802..87471050 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    90789843..90800066 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A411D538.1 GenPept UniProtKB/Swiss-Prot:A0A411D538

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials