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SORL1-AS1 SORL1 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 105369536, updated on 10-Oct-2023

Summary

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Official Symbol
SORL1-AS1provided by HGNC
Official Full Name
SORL1 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:55594
See related
AllianceGenome:HGNC:55594
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
51A
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
11q24.1
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (121438158..121452967, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (121464344..121479153, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4000 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:121165985-121166526 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:121166527-121167069 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4001 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5643 Neighboring gene sterol-C5-desaturase Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5644 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5645 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5646 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:121243330-121244107 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:121260007-121260508 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:121260509-121261008 Neighboring gene bone morphogenetic protein receptor type 1A pseudogene 2 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:121276805-121277684 Neighboring gene NANOG hESC enhancer GRCh37_chr11:121277972-121278473 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:121297351-121297863 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4002 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5647 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5648 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5649 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5650 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5651 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4003 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4004 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4005 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5655 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5654 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5652 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5653 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:121336477-121337676 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5657 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5658 Neighboring gene uncharacterized LOC105369535 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5659 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:121368848-121369348 Neighboring gene sortilin related receptor 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:121421721-121422920 Neighboring gene SORL1 eExon liver enhancer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5660 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5661 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:121441955-121442454 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:121441453-121441954 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4006 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5662 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:121465964-121467163 Neighboring gene Sharpr-MPRA regulatory region 6864 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:121507637-121508302 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:121508303-121508966 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:121514837-121515520 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5663 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:121543162-121543662 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:121559556-121560755 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5664 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:121673071-121673918 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:121694789-121695360 Neighboring gene uncharacterized LOC107984402

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples. Ciarlo E, et al. Dis Model Mech, 2013 Mar. PMID 22996644, Free PMC Article
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

Genotypes

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_183636.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000977, AP002365

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    121438158..121452967 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    121464344..121479153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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