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VPS11 VPS11 core subunit of CORVET and HOPS complexes [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105308858, updated on 30-Mar-2024

Summary

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Gene symbol
VPS11
Gene description
VPS11 core subunit of CORVET and HOPS complexes
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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See VPS11 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
27
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889414.1 (608310..626103)

NW_011889414.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S26-like Neighboring gene hypoxia up-regulated 1 Neighboring gene hydroxymethylbilane synthase Neighboring gene histone H2AX Neighboring gene dolichyl-phosphate N-acetylglucosaminephosphotransferase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011889414 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein-macromolecule adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endosome organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in organelle fusion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vacuole organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vesicle docking involved in exocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of HOPS complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vacuolar protein sorting-associated protein 11 homolog
Names
VPS11, CORVET/HOPS core subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011889414.1 Reference Pvam_2.0

    Range
    608310..626103
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011384899.2 → XP_011383201.1  vacuolar protein sorting-associated protein 11 homolog isoform X2

    UniProtKB/TrEMBL
    A0A6P3RUB9
    Conserved Domains (4) summary
    cd16688
    Location:820 → 863
    RING-H2_Vps11; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 11 homolog (Vps11) and similar proteins
    pfam00637
    Location:411 → 536
    Clathrin; Region in Clathrin and VPS
    pfam12451
    Location:864 → 907
    VPS11_C; Vacuolar protein sorting protein 11 C terminal
    cl29593
    Location:142 → 290
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_011384898.2 → XP_011383200.1  vacuolar protein sorting-associated protein 11 homolog isoform X1

    UniProtKB/TrEMBL
    A0A6P3S0R8
    Conserved Domains (5) summary
    smart00299
    Location:411 → 535
    CLH; Clathrin heavy chain repeat homology
    cd00162
    Location:863 → 902
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam00637
    Location:417 → 536
    Clathrin; Region in Clathrin and VPS
    pfam12451
    Location:904 → 949
    VPS11_C; Vacuolar protein sorting protein 11 C terminal
    cl02567
    Location:142 → 290
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version

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