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OCRL OCRL inositol polyphosphate-5-phosphatase [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105308304, updated on 30-Mar-2024

Summary

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Gene symbol
OCRL
Gene description
OCRL inositol polyphosphate-5-phosphatase
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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See OCRL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889347.1 (418497..473799)

NW_011889347.1Genomic Context describing neighboring genes Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 Neighboring gene phosphatidylinositol N-acetylglucosaminyltransferase subunit P pseudogene Neighboring gene uncharacterized LOC111733421 Neighboring gene 5S ribosomal RNA Neighboring gene piggyBac transposable element-derived protein 4-like Neighboring gene apelin

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011889347 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol phosphate phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inositol polyphosphate 5-phosphatase OCRL-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011889347.1 Reference Pvam_2.0

    Range
    418497..473799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023525480.1 → XP_023381248.1  inositol polyphosphate 5-phosphatase OCRL-1 isoform X1

    UniProtKB/TrEMBL
    A0A6P6C1H3
    Conserved Domains (3) summary
    cd09093
    Location:240 → 533
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:668 → 896
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    cd13382
    Location:11 → 115
    PH_OCRL1; oculocerebrorenal syndrome of Lowe 1 Pleckstrin homology-like domain

  2. XM_023525482.1 → XP_023381250.1  inositol polyphosphate 5-phosphatase OCRL-1 isoform X2

    UniProtKB/TrEMBL
    A0A6P6C279
    Conserved Domains (3) summary
    cd09093
    Location:239 → 532
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:667 → 895
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    cd13382
    Location:11 → 114
    PH_OCRL1; oculocerebrorenal syndrome of Lowe 1 Pleckstrin homology-like domain

  3. XM_023525483.1 → XP_023381251.1  inositol polyphosphate 5-phosphatase OCRL-1 isoform X3

    UniProtKB/TrEMBL
    A0A6P6C1H5
    Conserved Domains (3) summary
    cd09093
    Location:240 → 533
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:668 → 888
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    cd13382
    Location:11 → 115
    PH_OCRL1; oculocerebrorenal syndrome of Lowe 1 Pleckstrin homology-like domain
Nucleotide Protein
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