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BCAR1 BCAR1 scaffold protein, Cas family member [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105305354, updated on 11-Apr-2024

Summary

Gene symbol
BCAR1
Gene description
BCAR1 scaffold protein, Cas family member
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
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Genomic context

See BCAR1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889160.1 (583393..623794, complement)

NW_011889160.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111731493 Neighboring gene 5S ribosomal RNA Neighboring gene chymotrypsinogen 2-like Neighboring gene 5S ribosomal RNA Neighboring gene uncharacterized LOC111731502 Neighboring gene craniofacial development protein 1

Genomic regions, transcripts, and products

Genomic Sequence:
NW_011889160 Unplaced Scaffold Reference Pvam_2.0

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
breast cancer anti-estrogen resistance protein 1
Names
BCAR1, Cas family scaffold protein
BCAR1, Cas family scaffolding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011889160.1 Reference Pvam_2.0

    Range
    583393..623794 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011379935.2XP_011378237.1  breast cancer anti-estrogen resistance protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A6P3RAR1
    Conserved Domains (4) summary
    cd11552
    Location:451607
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:571
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    PHA03247
    Location:89419
    PHA03247; large tegument protein UL36; Provisional
    pfam12026
    Location:651861
    DUF3513; Domain of unknown function (DUF3513)
  2. XM_011379934.2XP_011378236.1  breast cancer anti-estrogen resistance protein 1 isoform X3

    See identical proteins and their annotated locations for XP_011378236.1

    UniProtKB/TrEMBL
    A0A6P3RJ51
    Conserved Domains (4) summary
    cd11552
    Location:455611
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:975
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    PHA03247
    Location:93423
    PHA03247; large tegument protein UL36; Provisional
    pfam12026
    Location:655865
    DUF3513; Domain of unknown function (DUF3513)
  3. XM_011379933.2XP_011378235.1  breast cancer anti-estrogen resistance protein 1 isoform X4

    See identical proteins and their annotated locations for XP_011378235.1

    UniProtKB/TrEMBL
    A0A6P3RJ51
    Conserved Domains (4) summary
    cd11552
    Location:455611
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:975
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    PHA03247
    Location:93423
    PHA03247; large tegument protein UL36; Provisional
    pfam12026
    Location:655865
    DUF3513; Domain of unknown function (DUF3513)
  4. XM_023523146.1XP_023378914.1  breast cancer anti-estrogen resistance protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A6P6BV25
    Conserved Domains (4) summary
    cd11552
    Location:519675
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd11569
    Location:770902
    FAT-like_BCAR1_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:73139
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    cl26464
    Location:157487
    Atrophin-1; Atrophin-1 family
  5. XM_023523145.1XP_023378913.1  breast cancer anti-estrogen resistance protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A6P6BUX0
    Conserved Domains (4) summary
    cd11552
    Location:519675
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd11569
    Location:800932
    FAT-like_BCAR1_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:73139
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    cl26464
    Location:157496
    Atrophin-1; Atrophin-1 family