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CDKN1B cyclin dependent kinase inhibitor 1B [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105302792, updated on 30-Mar-2024

Summary

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Gene symbol
CDKN1B
Gene description
cyclin dependent kinase inhibitor 1B
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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See CDKN1B in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889064.1 (1741274..1746321, complement)

NW_011889064.1Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene apolipoprotein L domain containing 1 Neighboring gene 5S ribosomal RNA Neighboring gene G protein-coupled receptor 19 Neighboring gene cAMP responsive element binding protein like 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011889064 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel mutation in the upstream open reading frame of the CDKN1B gene causes a MEN4 phenotype. Occhi G, et al. PLoS Genet, 2013 Mar. PMID 23555276, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein-folding chaperone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cyclin-dependent kinase inhibitor 1B
Names
p27 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305195.1 → NP_001292124.1  cyclin-dependent kinase inhibitor 1B

    See identical proteins and their annotated locations for NP_001292124.1

    Status: PROVISIONAL

    Source sequence(s)
    HE804771
    UniProtKB/TrEMBL
    N0DX52
    Conserved Domains (1) summary
    pfam02234
    Location:32 → 77
    CDI; Cyclin-dependent kinase inhibitor

RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011889064.1 Reference Pvam_2.0

    Range
    1741274..1746321 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011376010.2 → XP_011374312.1  cyclin-dependent kinase inhibitor 1B isoform X1

    See identical proteins and their annotated locations for XP_011374312.1

    UniProtKB/TrEMBL
    N0DX52
    Conserved Domains (1) summary
    pfam02234
    Location:32 → 77
    CDI; Cyclin-dependent kinase inhibitor
Nucleotide Protein
Heading Accession and Version

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