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SHMT2 serine hydroxymethyltransferase 2 [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105302550, updated on 30-Mar-2024

Summary

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Gene symbol
SHMT2
Gene description
serine hydroxymethyltransferase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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See SHMT2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889057.1 (97687..102976, complement)

NW_011889057.1Genomic Context describing neighboring genes Neighboring gene R3H domain containing 2 Neighboring gene SH3 and cysteine rich domain 3 Neighboring gene uncharacterized LOC111729703 Neighboring gene NDUFA4 mitochondrial complex associated like 2 Neighboring gene neurexophilin 4 Neighboring gene LDL receptor related protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011889057 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cobalt ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glycine hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA 5'-UTR binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA regulatory element binding translation repressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-serine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in folic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein homotetramerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in purine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of oxidative phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to type I interferon IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of BRISC complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine hydroxymethyltransferase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011889057.1 Reference Pvam_2.0

    Range
    97687..102976 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011375621.2 → XP_011373923.1  serine hydroxymethyltransferase, mitochondrial

    See identical proteins and their annotated locations for XP_011373923.1

    UniProtKB/TrEMBL
    A0A6P3RH85
    Conserved Domains (1) summary
    PLN03226
    Location:36 → 502
    PLN03226; serine hydroxymethyltransferase; Provisional
Nucleotide Protein
Heading Accession and Version

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