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HMGCLL1 3-hydroxy-3-methylglutaryl-CoA lyase like 1 [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105302076, updated on 11-Apr-2024

Summary

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Gene symbol
HMGCLL1
Gene description
3-hydroxy-3-methylglutaryl-CoA lyase like 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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See HMGCLL1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889041.1 (1562864..1730242)

NW_011889041.1Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein 5 Neighboring gene 5S ribosomal RNA Neighboring gene 60S ribosomal protein L23a pseudogene Neighboring gene 5S ribosomal RNA Neighboring gene GDNF family receptor alpha like Neighboring gene hypocretin receptor 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011889041 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ketone body biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic
Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase L1
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011889041.1 Reference Pvam_2.0

    Range
    1562864..1730242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011375015.1 → XP_011373317.1  3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X1

    UniProtKB/TrEMBL
    A0A6P3R037
    Conserved Domains (2) summary
    PLN02746
    Location:41 → 336
    PLN02746; hydroxymethylglutaryl-CoA lyase
    pfam00682
    Location:48 → 321
    HMGL-like; HMGL-like

  2. XM_011375019.1 → XP_011373321.1  3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X4

    UniProtKB/TrEMBL
    A0A6P3RFP1
    Conserved Domains (1) summary
    cl21457
    Location:41 → 233
    TIM; TIM-like beta/alpha barrel domains

  3. XM_011375017.1 → XP_011373319.1  3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X3

    UniProtKB/TrEMBL
    A0A6P3R2F9
    Conserved Domains (1) summary
    cl21457
    Location:41 → 304
    TIM; TIM-like beta/alpha barrel domains

  4. XM_011375016.1 → XP_011373318.1  3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X2

    UniProtKB/TrEMBL
    A0A6P3R112
    Conserved Domains (2) summary
    PLN02746
    Location:62 → 366
    PLN02746; hydroxymethylglutaryl-CoA lyase
    pfam00682
    Location:78 → 351
    HMGL-like; HMGL-like
Nucleotide Protein
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