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SIRT1 sirtuin 1 [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105301705, updated on 30-Mar-2024

Summary

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Gene symbol
SIRT1
Gene description
sirtuin 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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See SIRT1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889030.1 (2038236..2067562)

NW_011889030.1Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C12 Neighboring gene eukaryotic translation initiation factor 3 subunit L pseudogene Neighboring gene 5S ribosomal RNA Neighboring gene HECT and RLD domain containing E3 ubiquitin protein ligase 4 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011889030 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NAD-dependent protein deacetylase sirtuin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011889030.1 Reference Pvam_2.0

    Range
    2038236..2067562
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011374482.2 → XP_011372784.1  NAD-dependent protein deacetylase sirtuin-1 isoform X1

    UniProtKB/TrEMBL
    A0A6P3R1D9
    Conserved Domains (1) summary
    cd01408
    Location:246 → 481
    SIRT1; SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 ...

  2. XM_023520123.1 → XP_023375891.1  NAD-dependent protein deacetylase sirtuin-1 isoform X2

    UniProtKB/TrEMBL
    A0A6P6BLE7
    Conserved Domains (1) summary
    cl00195
    Location:12 → 186
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...
Nucleotide Protein
Heading Accession and Version

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