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FASN fatty acid synthase [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105301128, updated on 30-Mar-2024

Summary

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Gene symbol
FASN
Gene description
fatty acid synthase
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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See FASN in Genome Data Viewer
Location:
chromosome: Un
Exon count:
42
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889008.1 (716248..733261)

NW_011889008.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 57 Neighboring gene 5S ribosomal RNA Neighboring gene 5S ribosomal RNA Neighboring gene dihydrouridine synthase 1 like Neighboring gene G protein pathway suppressor 1 Neighboring gene RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011889008 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3-oxoacyl-[acyl-carrier-protein] synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fatty acid synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphopantetheine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fatty acid synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011889008.1 Reference Pvam_2.0

    Range
    716248..733261
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023538614.1 → XP_023394382.1  fatty acid synthase

    UniProtKB/TrEMBL
    A0A6P6D4B0
    Conserved Domains (7) summary
    cd08954
    Location:1879 → 2115
    KR_1_FAS_SDR_x; beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 1, complex (x) SDRs
    smart00823
    Location:2128 → 2183
    PKS_PP; Phosphopantetheine attachment site
    smart00829
    Location:1570 → 1857
    PKS_ER; Enoylreductase
    COG3321
    Location:1 → 1018
    PksD; Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism]
    cd00833
    Location:2 → 404
    PKS; polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or ...
    pfam08242
    Location:1246 → 1345
    Methyltransf_12; Methyltransferase domain
    cl21494
    Location:2242 → 2501
    Abhydrolase; alpha/beta hydrolases

  2. XM_011373663.2 → XP_011371965.1  fatty acid synthase

    UniProtKB/TrEMBL
    A0A6P6D4B0
    Conserved Domains (7) summary
    cd08954
    Location:1879 → 2115
    KR_1_FAS_SDR_x; beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 1, complex (x) SDRs
    smart00823
    Location:2128 → 2183
    PKS_PP; Phosphopantetheine attachment site
    smart00829
    Location:1570 → 1857
    PKS_ER; Enoylreductase
    COG3321
    Location:1 → 1018
    PksD; Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism]
    cd00833
    Location:2 → 404
    PKS; polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or ...
    pfam08242
    Location:1246 → 1345
    Methyltransf_12; Methyltransferase domain
    cl21494
    Location:2242 → 2501
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
Heading Accession and Version

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