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PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [ Camelus dromedarius (Arabian camel) ]

Gene ID: 105086305, updated on 19-Apr-2024

Summary

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Gene symbol
PIK3CB
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Locus tag
Cadr_000000171
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus dromedarius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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See PIK3CB in Genome Data Viewer
Location:
chromosome: 2
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_04 current mCamDro1.pat (GCF_036321535.1) 2 NC_087437.1 (18695739..18845408, complement)
101 previous assembly CamDro3 (GCF_000803125.2) 1 NC_044511.1 (16545648..16695280, complement)

Chromosome 2 - NC_087437.1Genomic Context describing neighboring genes Neighboring gene centrosomal protein 70 Neighboring gene transfer RNA alanine (anticodon GGC) Neighboring gene Fas apoptotic inhibitory molecule Neighboring gene small nucleolar RNA ACA64 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12-like Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC135318802

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Names
Phosphatidylinositol 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036321535.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCamDro1.pat

Genomic

  1. NC_087437.1 Reference mCamDro1.pat

    Range
    18695739..18845408 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031443314.2 → XP_031299174.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

    Conserved Domains (5) summary
    cd08693
    Location:324 → 501
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00143
    Location:41 → 118
    PI3K_p85B; PI3-kinase family, p85-binding domain
    cd00872
    Location:532 → 702
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:706 → 1067
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:180 → 288
    PI3K_rbd; PI3-kinase family, ras-binding domain
Nucleotide Protein
Heading Accession and Version

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