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parp1 poly (ADP-ribose) polymerase 1 [ Esox lucius (northern pike) ]

Gene ID: 105006604, updated on 18-Sep-2024

Summary

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Gene symbol
parp1
Gene description
poly (ADP-ribose) polymerase 1
See related
Ensembl:ENSELUG00000017336
Gene type
protein coding
RefSeq status
MODEL
Organism
Esox lucius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes; Esocidae; Esox
Orthologs
human zebrafish all
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Genomic context

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See parp1 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
21
Annotation release Status Assembly Chr Location
104 current fEsoLuc1.pri (GCF_011004845.1) 18 NC_047586.1 (26804824..26819694)
103 previous assembly Eluc_v4 (GCF_004634155.1) Linkage Group LG18 NC_025985.4 (26833288..26847657)

Chromosome 18 - NC_047586.1Genomic Context describing neighboring genes Neighboring gene pro-opiomelanocortin Neighboring gene uncharacterized LOC105009778 Neighboring gene protein EFR3 homolog B Neighboring gene adenosine receptor A2a-like Neighboring gene lin-9 DREAM MuvB core complex component Neighboring gene Mix paired-like homeobox

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NAD+-protein poly-ADP-ribosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
poly [ADP-ribose] polymerase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Esox lucius Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fEsoLuc1.pri Primary Assembly

Genomic

  1. NC_047586.1 Reference fEsoLuc1.pri Primary Assembly

    Range
    26804824..26819694
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010865231.5 → XP_010863533.1  poly [ADP-ribose] polymerase 1

    UniProtKB/TrEMBL
    A0A3P8YM69, A0A6Q2ZKK7
    Related
    ENSELUP00000017644.2, ENSELUT00000040267.3
    Conserved Domains (6) summary
    cd08001
    Location:540 → 642
    WGR_PARP1_like; WGR domain of poly(ADP-ribose) polymerase 1 and similar proteins
    PLN03123
    Location:7 → 1007
    PLN03123; poly [ADP-ribose] polymerase; Provisional
    cd01437
    Location:659 → 1003
    parp_like; Poly(ADP-ribose) polymerase (parp) catalytic domain catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a ...
    pfam00533
    Location:386 → 459
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam00645
    Location:13 → 86
    zf-PARP; Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
    pfam08063
    Location:276 → 327
    PADR1; PADR1 (NUC008) domain
Nucleotide Protein
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