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EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 [ Bison bison bison ]

Gene ID: 104998072, updated on 12-Mar-2024

Summary

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Gene symbol
EDEM3
Gene description
ER degradation enhancing alpha-mannosidase like protein 3
See related
Ensembl:ENSBBBG00000000431
Gene type
protein coding
RefSeq status
MODEL
Organism
Bison bison bison (sub-species: bison)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bison
Orthologs
human mouse all
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Genomic context

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See EDEM3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
100 current Bison_UMD1.0 (GCF_000754665.1) Unplaced Scaffold NW_011494894.1 (6201407..6267331)

NW_011494894.1Genomic Context describing neighboring genes Neighboring gene niban apoptosis regulator 1 Neighboring gene polyadenylate-binding protein-interacting protein 1 pseudogene Neighboring gene HIG1 domain family member 1A, mitochondrial pseudogene Neighboring gene chromosome unknown open reading frame, human C1orf21

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011494894.1 Unplaced Scaffold Reference Bison_UMD1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endoplasmic reticulum mannose trimming IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mannose trimming involved in glycoprotein ERAD pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ER degradation-enhancing alpha-mannosidase-like protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bison bison bison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bison_UMD1.0 Primary Assembly

Genomic

  1. NW_011494894.1 Reference Bison_UMD1.0 Primary Assembly

    Range
    6201407..6267331
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010853088.1 → XP_010851390.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A6P3IK56
    Conserved Domains (2) summary
    cd02126
    Location:607 → 732
    PA_EDEM3_like; PA_EDEM3_like: protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar ...
    pfam01532
    Location:1 → 440
    Glyco_hydro_47; Glycosyl hydrolase family 47

  2. XM_010853090.1 → XP_010851392.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A6P3IHM8
    Conserved Domains (2) summary
    cd02126
    Location:588 → 713
    PA_EDEM3_like; PA_EDEM3_like: protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar ...
    pfam01532
    Location:1 → 440
    Glyco_hydro_47; Glycosyl hydrolase family 47

  3. XM_010853089.1 → XP_010851391.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A6P3IA17
    Related
    ENSBBBP00000027037.1, ENSBBBT00000026321.1
    Conserved Domains (2) summary
    cd02126
    Location:606 → 731
    PA_EDEM3_like; PA_EDEM3_like: protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar ...
    pfam01532
    Location:1 → 440
    Glyco_hydro_47; Glycosyl hydrolase family 47
Nucleotide Protein
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