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ALOX12B arachidonate 12-lipoxygenase, 12R type [ Bison bison bison ]

Gene ID: 104990750, updated on 12-Mar-2024

Summary

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Gene symbol
ALOX12B
Gene description
arachidonate 12-lipoxygenase, 12R type
See related
Ensembl:ENSBBBG00000012570
Gene type
protein coding
RefSeq status
MODEL
Organism
Bison bison bison (sub-species: bison)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bison
Orthologs
human mouse all
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Genomic context

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See ALOX12B in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100 current Bison_UMD1.0 (GCF_000754665.1) Unplaced Scaffold NW_011494752.1 (15565044..15576802)

NW_011494752.1Genomic Context describing neighboring genes Neighboring gene transfer RNA leucine (anticodon UAG) Neighboring gene hes family bHLH transcription factor 7 Neighboring gene arachidonate epidermal lipoxygenase 3 Neighboring gene arachidonate 15-lipoxygenase B-like Neighboring gene arachidonate 15-lipoxygenase B-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011494752.1 Unplaced Scaffold Reference Bison_UMD1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 12(S)-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 12-lipoxygenase, 12R-type

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bison bison bison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bison_UMD1.0 Primary Assembly

Genomic

  1. NW_011494752.1 Reference Bison_UMD1.0 Primary Assembly

    Range
    15565044..15576802
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010843056.1 → XP_010841358.1  arachidonate 12-lipoxygenase, 12R-type

    UniProtKB/TrEMBL
    A0A6P3HEF3
    Related
    ENSBBBP00000019264.1, ENSBBBT00000009852.1
    Conserved Domains (2) summary
    cd01753
    Location:2 → 116
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:218 → 679
    Lipoxygenase; Lipoxygenase
Nucleotide Protein
Heading Accession and Version

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