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PLCB1 phospholipase C beta 1 [ Bison bison bison ]

Gene ID: 104984486, updated on 12-Mar-2024

Summary

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Gene symbol
PLCB1
Gene description
phospholipase C beta 1
See related
Ensembl:ENSBBBG00000001930
Gene type
protein coding
RefSeq status
MODEL
Organism
Bison bison bison (sub-species: bison)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bison
Orthologs
human mouse all
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Genomic context

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See PLCB1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
31
Annotation release Status Assembly Chr Location
100 current Bison_UMD1.0 (GCF_000754665.1) Unplaced Scaffold NW_011494602.1 (3959281..4793078, complement)

NW_011494602.1Genomic Context describing neighboring genes Neighboring gene lysosomal associated membrane protein family member 5 Neighboring gene phospholipase C beta 4 Neighboring gene uncharacterized LOC104984485 Neighboring gene thioredoxin-related transmembrane protein 4-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011494602.1 Unplaced Scaffold Reference Bison_UMD1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in memory IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bison bison bison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bison_UMD1.0 Primary Assembly

Genomic

  1. NW_011494602.1 Reference Bison_UMD1.0 Primary Assembly

    Range
    3959281..4793078 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010834232.1 → XP_010832534.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

    UniProtKB/TrEMBL
    A0A6P3H076
    Related
    ENSBBBP00000003060.1, ENSBBBT00000010661.1
    Conserved Domains (7) summary
    cd00275
    Location:576 → 695
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:215 → 542
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02952
    Location:115 → 683
    PLN02952; phosphoinositide phospholipase C
    pfam06631
    Location:802 → 838
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:902 → 1071
    PLC-beta_C; PLC-beta C terminal
    pfam09279
    Location:123 → 213
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    cl17171
    Location:1 → 47
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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