U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial [ Bison bison bison ]

Gene ID: 104982022, updated on 12-Mar-2024

Summary

Gene symbol
PCK2
Gene description
phosphoenolpyruvate carboxykinase 2, mitochondrial
See related
Ensembl:ENSBBBG00000022045
Gene type
protein coding
RefSeq status
MODEL
Organism
Bison bison bison (sub-species: bison)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bison
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See PCK2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current Bison_UMD1.0 (GCF_000754665.1) Unplaced Scaffold NW_011495077.1 (2552162..2560574)

NW_011495077.1Genomic Context describing neighboring genes Neighboring gene copine 6 Neighboring gene neural retina leucine zipper Neighboring gene DDB1 and CUL4 associated factor 11 Neighboring gene DDB1- and CUL4-associated factor 11-like Neighboring gene fat storage inducing transmembrane protein 1

Genomic regions, transcripts, and products

Genomic Sequence:
NW_011495077.1 Unplaced Scaffold Reference Bison_UMD1.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phosphoenolpyruvate carboxykinase (GTP) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to dexamethasone stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycerol biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in hepatocyte differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in propionate catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to starvation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
phosphoenolpyruvate carboxykinase [GTP], mitochondrial

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Bison bison bison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bison_UMD1.0 Primary Assembly

Genomic

  1. NW_011495077.1 Reference Bison_UMD1.0 Primary Assembly

    Range
    2552162..2560574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010831312.1XP_010829614.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial

    UniProtKB/TrEMBL
    A0A6P3GRY2
    Related
    ENSBBBP00000026297.1, ENSBBBT00000024772.1
    Conserved Domains (1) summary
    cd00819
    Location:44633
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...