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HSPG2 heparan sulfate proteoglycan 2 [ Bison bison bison ]

Gene ID: 104981234, updated on 12-Mar-2024

Summary

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Gene symbol
HSPG2
Gene description
heparan sulfate proteoglycan 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Bison bison bison (sub-species: bison)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bison
Orthologs
human mouse all
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Genomic context

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See HSPG2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
97
Annotation release Status Assembly Chr Location
100 current Bison_UMD1.0 (GCF_000754665.1) Unplaced Scaffold NW_011495069.1 (4498092..4580393, complement)

NW_011495069.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 48 Neighboring gene low density lipoprotein receptor class A domain containing 2 Neighboring gene uncharacterized LOC104981083 Neighboring gene uncharacterized LOC104981084

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011495069.1 Unplaced Scaffold Reference Bison_UMD1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: basement membrane-specific heparan sulfate proteoglycan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bison bison bison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bison_UMD1.0 Primary Assembly

Genomic

  1. NW_011495069.1 Reference Bison_UMD1.0 Primary Assembly

    Range
    4498092..4580393 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010830236.1 → XP_010828538.1  LOW QUALITY PROTEIN: basement membrane-specific heparan sulfate proteoglycan core protein

    UniProtKB/TrEMBL
    A0A6P3GA92
    Conserved Domains (17) summary
    cd05754
    Location:1672 → 1757
    Ig3_Perlecan_like; Third immunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00192
    Location:312 → 340
    LDLa; Low-density lipoprotein receptor domain class A
    smart00408
    Location:2571 → 2630
    IGc2; Immunoglobulin C-2 Type
    smart00281
    Location:1296 → 1417
    LamB; Laminin B domain
    smart00409
    Location:3147 → 3221
    IG; Immunoglobulin
    smart00410
    Location:1584 → 1664
    IG_like; Immunoglobulin like
    cd00054
    Location:3778 → 3807
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1101 → 1150
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:4135 → 4294
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:367 → 402
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:3502 → 3584
    I-set; Immunoglobulin I-set domain
    pfam00047
    Location:2953 → 3033
    ig; Immunoglobulin domain
    pfam00053
    Location:1219 → 1266
    Laminin_EGF; Laminin EGF domain
    pfam13895
    Location:2856 → 2936
    Ig_2; Immunoglobulin domain
    cl02507
    Location:133 → 241
    SEA; SEA domain
    cl02548
    Location:574 → 659
    Laminin_B; Laminin B (Domain IV)
    cl11960
    Location:424 → 482
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version

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