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CAP1 cyclase associated actin cytoskeleton regulatory protein 1 [ Homo sapiens (human) ]

Gene ID: 10487, updated on 7-Apr-2024

Summary

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Official Symbol
CAP1provided by HGNC
Official Full Name
cyclase associated actin cytoskeleton regulatory protein 1provided by HGNC
Primary source
HGNC:HGNC:20040
See related
Ensembl:ENSG00000131236 MIM:617801; AllianceGenome:HGNC:20040
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CAP; CAP1-PEN
Summary
The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2016]
Expression
Ubiquitous expression in appendix (RPKM 105.5), lymph node (RPKM 89.3) and 25 other tissues See more
Orthologs
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Genomic context

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See CAP1 in Genome Data Viewer
Location:
1p34.2
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (40040240..40072648)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (39909560..39942077)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (40505912..40538320)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:40363871-40364442 Neighboring gene MYCL antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 6057 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 714 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 715 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 716 Neighboring gene MYCL proto-oncogene, bHLH transcription factor Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:40409912-40410434 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 717 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 823 Neighboring gene MFSD2 lysolipid transporter A, lysophospholipid Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:40446045-40446898 Neighboring gene ribosomal protein S2 pseudogene 12 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 718 Neighboring gene uncharacterized LOC105378669 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 719 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 824 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:40505419-40506052 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:40506053-40506687 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:40518723-40519222 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:40524580-40525341 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:40535511-40536710 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 720 Neighboring gene Sharpr-MPRA regulatory region 13734 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 829 Neighboring gene palmitoyl-protein thioesterase 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:40598557-40599056 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 830 Neighboring gene uncharacterized LOC105378671 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 831 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 721 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:40625521-40625722 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:40626731-40627347 Neighboring gene OAZ1 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Phosphorylation of CAP1 regulates lung cancer proliferation, migration, and invasion. Zeng J, et al. J Cancer Res Clin Oncol, 2022 Jan. PMID 34636991, Free PMC Article
  2. Novel role of CAP1 in regulation RNA polymerase II-mediated transcription elongation depends on its actin-depolymerization activity in nucleoplasm. Zhang Q, et al. Oncogene, 2021 May. PMID 33911205
  3. Effects of tumor-specific CAP1 expression and body constitution on clinical outcomes in patients with early breast cancer. Bergqvist M, et al. Breast Cancer Res, 2020 Jun 19. PMID 32560703, Free PMC Article
  4. Dynamic Phosphorylation and Dephosphorylation of Cyclase-Associated Protein 1 by Antagonistic Signaling through Cyclin-Dependent Kinase 5 and cAMP Are Critical for the Protein Functions in Actin Filament Disassembly and Cell Adhesion. Zhang H, et al. Mol Cell Biol, 2020 Jan 30. PMID 31791978, Free PMC Article
  5. Serum Resistin, Adenylate Cyclase-Associated Protein 1 Gene Expression, and Carotid Intima-Media Thickness in Patients with End-Stage Renal Disease and Healthy Controls. Munjas J, et al. Cardiorenal Med, 2020. PMID 31722350

See all (129) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mutual functional dependence of cyclase-associated protein 1 (CAP1) and cofilin1 in neuronal actin dynamics and growth cone function.
    Title: Mutual functional dependence of cyclase-associated protein 1 (CAP1) and cofilin1 in neuronal actin dynamics and growth cone function.
  2. Phosphorylation of CAP1 regulates lung cancer proliferation, migration, and invasion.
    Title: Phosphorylation of CAP1 regulates lung cancer proliferation, migration, and invasion.
  3. Serum levels of cytoskeleton remodeling proteins and their mRNA expression in tumor tissue of metastatic laryngeal and hypopharyngeal cancers.
    Title: Serum levels of cytoskeleton remodeling proteins and their mRNA expression in tumor tissue of metastatic laryngeal and hypopharyngeal cancers.
  4. Novel role of CAP1 in regulation RNA polymerase II-mediated transcription elongation depends on its actin-depolymerization activity in nucleoplasm.
    Title: Novel role of CAP1 in regulation RNA polymerase II-mediated transcription elongation depends on its actin-depolymerization activity in nucleoplasm.
  5. Relationship of intracellular proteolysis with CAP1 and cofilin1 in non-small-cell lung cancer.
    Title: Relationship of intracellular proteolysis with CAP1 and cofilin1 in non-small-cell lung cancer.
  6. Serum Resistin, Adenylate Cyclase-Associated Protein 1 Gene Expression, and Carotid Intima-Media Thickness in Patients with End-Stage Renal Disease and Healthy Controls.
    Title: Serum Resistin, Adenylate Cyclase-Associated Protein 1 Gene Expression, and Carotid Intima-Media Thickness in Patients with End-Stage Renal Disease and Healthy Controls.
  7. Effects of tumor-specific CAP1 expression and body constitution on clinical outcomes in patients with early breast cancer.
    Title: Effects of tumor-specific CAP1 expression and body constitution on clinical outcomes in patients with early breast cancer.
  8. Phosphorylation Regulates CAP1 (Cyclase-Associated Protein 1) Functions in the Motility and Invasion of Pancreatic Cancer Cells.
    Title: Phosphorylation Regulates CAP1 (Cyclase-Associated Protein 1) Functions in the Motility and Invasion of Pancreatic Cancer Cells.
  9. Resistin induces breast cancer cells epithelial to mesenchymal transition (EMT) and stemness through both adenylyl cyclase-associated protein 1 (CAP1)-dependent and CAP1-independent mechanisms.
    Title: Resistin induces breast cancer cells epithelial to mesenchymal transition (EMT) and stemness through both adenylyl cyclase-associated protein 1 (CAP1)-dependent and CAP1-independent mechanisms.
  10. this study provides direct cellular evidence that transient phosphorylation is required for CAP1 functions in both actin filament turnover and adhesion, and the novel mechanistic insights substantially extend our knowledge of the cell signals that function in concert to regulate CAP1 by facilitating its transient phosphorylation.
    Title: Dynamic Phosphorylation and Dephosphorylation of Cyclase-Associated Protein 1 by Antagonistic Signaling through Cyclin-Dependent Kinase 5 and cAMP Are Critical for the Protein Functions in Actin Filament Disassembly and Cell Adhesion.
Submit: New GeneRIF Correction See all GeneRIFs (36)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables actin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables adenylate cyclase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in activation of adenylate cyclase activity TAS
Traceable Author Statement
more info
 PubMed 
involved_in ameboidal-type cell migration IEA
Inferred from Electronic Annotation
more info
  
involved_in cAMP-mediated signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in establishment or maintenance of cell polarity TAS
Traceable Author Statement
more info
 PubMed 
involved_in receptor-mediated endocytosis IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in azurophil granule lumen TAS
Traceable Author Statement
more info
  
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular exosome HDA PubMed 
located_in extracellular region TAS
Traceable Author Statement
more info
  
located_in focal adhesion HDA PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
adenylyl cyclase-associated protein 1
Names
CAP, adenylate cyclase-associated protein 1
adenylate cyclase associated protein 1
testis secretory sperm-binding protein Li 218p

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105530.2 → NP_001099000.2  adenylyl cyclase-associated protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 4-10 encode the same isoform (a).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS41309.1
    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6
    UniProtKB/TrEMBL
    B2RDY9
    Related
    ENSP00000361883.3, ENST00000372797.7
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 62
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:319 → 473
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  2. NM_001330502.2 → NP_001317431.2  adenylyl cyclase-associated protein 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is 1 aa shorter compared to isoform a. Variants 3 and 11-14 encode the same isoform (b).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS81304.1
    UniProtKB/TrEMBL
    B2RDY9
    Related
    ENSP00000344832.3, ENST00000340450.7
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 61
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:318 → 472
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  3. NM_001350475.2 → NP_001337404.2  adenylyl cyclase-associated protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 4-10 encode the same isoform (a).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS41309.1
    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6
    UniProtKB/TrEMBL
    B2RDY9
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 62
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:319 → 473
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  4. NM_001350476.2 → NP_001337405.2  adenylyl cyclase-associated protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 4-10 encode the same isoform (a).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS41309.1
    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6
    UniProtKB/TrEMBL
    B2RDY9
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 62
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:319 → 473
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  5. NM_001350477.3 → NP_001337406.2  adenylyl cyclase-associated protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 4-10 encode the same isoform (a).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS41309.1
    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6
    UniProtKB/TrEMBL
    B2RDY9
    Related
    ENSP00000361878.2, ENST00000372792.7
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 62
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:319 → 473
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  6. NM_001350478.2 → NP_001337407.2  adenylyl cyclase-associated protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 4-10 encode the same isoform (a).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS41309.1
    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6
    UniProtKB/TrEMBL
    B2RDY9
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 62
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:319 → 473
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  7. NM_001350479.2 → NP_001337408.2  adenylyl cyclase-associated protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 4-10 encode the same isoform (a).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS41309.1
    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6
    UniProtKB/TrEMBL
    B2RDY9
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 62
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:319 → 473
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  8. NM_001350480.2 → NP_001337409.2  adenylyl cyclase-associated protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 4-10 encode the same isoform (a).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS41309.1
    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6
    UniProtKB/TrEMBL
    B2RDY9
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 62
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:319 → 473
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  9. NM_001350481.2 → NP_001337410.2  adenylyl cyclase-associated protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 4-10 encode the same isoform (a).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS41309.1
    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6
    UniProtKB/TrEMBL
    B2RDY9
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 62
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:319 → 473
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  10. NM_001350482.2 → NP_001337411.2  adenylyl cyclase-associated protein 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is 1 aa shorter compared to isoform a. Variants 3 and 11-14 encode the same isoform (b).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS81304.1
    UniProtKB/TrEMBL
    B2RDY9
    Related
    ENSP00000361884.1, ENST00000372798.5
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 61
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:318 → 472
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  11. NM_001350483.2 → NP_001337412.2  adenylyl cyclase-associated protein 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is 1 aa shorter compared to isoform a. Variants 3 and 11-14 encode the same isoform (b).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS81304.1
    UniProtKB/TrEMBL
    B2RDY9
    Related
    ENSP00000361888.1, ENST00000372802.5
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 61
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:318 → 472
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  12. NM_001350484.2 → NP_001337413.2  adenylyl cyclase-associated protein 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is 1 aa shorter compared to isoform a. Variants 3 and 11-14 encode the same isoform (b).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS81304.1
    UniProtKB/TrEMBL
    B2RDY9
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 61
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:318 → 472
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  13. NM_001350485.2 → NP_001337414.2  adenylyl cyclase-associated protein 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is 1 aa shorter compared to isoform a. Variants 3 and 11-14 encode the same isoform (b).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS81304.1
    UniProtKB/TrEMBL
    B2RDY9
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 61
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:318 → 472
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  14. NM_006367.4 → NP_006358.2  adenylyl cyclase-associated protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a). Variants 1, 2, and 4-10 encode the same isoform (a).
    Source sequence(s)
    AL512599
    Consensus CDS
    CCDS41309.1
    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6
    UniProtKB/TrEMBL
    B2RDY9
    Related
    ENSP00000361891.3, ENST00000372805.8
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 62
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:319 → 473
    CAP_C; Adenylate cyclase associated (CAP) C terminal

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    40040240..40072648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047431628.1 → XP_047287584.1  adenylyl cyclase-associated protein 1 isoform X2

  2. XM_047431636.1 → XP_047287592.1  adenylyl cyclase-associated protein 1 isoform X2

  3. XM_047431520.1 → XP_047287476.1  adenylyl cyclase-associated protein 1 isoform X2

  4. XM_047431420.1 → XP_047287376.1  adenylyl cyclase-associated protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6

  5. XM_011540515.2 → XP_011538817.1  adenylyl cyclase-associated protein 1 isoform X2

    See identical proteins and their annotated locations for XP_011538817.1

    UniProtKB/TrEMBL
    B2RDY9
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 61
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:318 → 472
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  6. XM_011540510.2 → XP_011538812.1  adenylyl cyclase-associated protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011538812.1

    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6
    UniProtKB/TrEMBL
    B2RDY9
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 62
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:319 → 473
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  7. XM_047431603.1 → XP_047287559.1  adenylyl cyclase-associated protein 1 isoform X2

  8. XM_017000069.2 → XP_016855558.1  adenylyl cyclase-associated protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6
    UniProtKB/TrEMBL
    B2RDY9
    Conserved Domains (2) summary
    pfam01213
    Location:5 → 62
    CAP_N; Adenylate cyclase associated (CAP) N terminal
    pfam08603
    Location:319 → 473
    CAP_C; Adenylate cyclase associated (CAP) C terminal

  9. XM_047431580.1 → XP_047287536.1  adenylyl cyclase-associated protein 1 isoform X2

  10. XM_047431489.1 → XP_047287445.1  adenylyl cyclase-associated protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q01518, Q53HR7, Q5T0S1, Q5T0S2, Q6I9U6

  11. XM_047431616.1 → XP_047287572.1  adenylyl cyclase-associated protein 1 isoform X2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    39909560..39942077
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333863.1 → XP_054189838.1  adenylyl cyclase-associated protein 1 isoform X2

  2. XM_054333864.1 → XP_054189839.1  adenylyl cyclase-associated protein 1 isoform X2

  3. XM_054333858.1 → XP_054189833.1  adenylyl cyclase-associated protein 1 isoform X2

  4. XM_054333854.1 → XP_054189829.1  adenylyl cyclase-associated protein 1 isoform X1

    UniProtKB/TrEMBL
    D3DPU2

  5. XM_054333859.1 → XP_054189834.1  adenylyl cyclase-associated protein 1 isoform X2

  6. XM_054333856.1 → XP_054189831.1  adenylyl cyclase-associated protein 1 isoform X1

    UniProtKB/TrEMBL
    D3DPU2

  7. XM_054333861.1 → XP_054189836.1  adenylyl cyclase-associated protein 1 isoform X2

  8. XM_054333855.1 → XP_054189830.1  adenylyl cyclase-associated protein 1 isoform X1

    UniProtKB/TrEMBL
    D3DPU2

  9. XM_054333860.1 → XP_054189835.1  adenylyl cyclase-associated protein 1 isoform X2

  10. XM_054333857.1 → XP_054189832.1  adenylyl cyclase-associated protein 1 isoform X1

    UniProtKB/TrEMBL
    D3DPU2

  11. XM_054333862.1 → XP_054189837.1  adenylyl cyclase-associated protein 1 isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q01518.5 GenPept UniProtKB/Swiss-Prot:Q01518

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