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Eif2ak2 eukaryotic translation initiation factor 2 alpha kinase 2 [ Fukomys damarensis (Damara mole-rat) ]

Gene ID: 104853460, updated on 12-Mar-2024

Summary

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Gene symbol
Eif2ak2
Gene description
eukaryotic translation initiation factor 2 alpha kinase 2
Locus tag
H920_18277
See related
Ensembl:ENSFDAG00000006052
Gene type
protein coding
RefSeq status
MODEL
Organism
Fukomys damarensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Fukomys
Orthologs
human mouse all
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Genomic context

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See Eif2ak2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
102 current DMR_v1.0_HiC (GCF_012274545.1) Unplaced Scaffold NW_022900914.1 (16983883..17023457, complement)
101 previous assembly DMR_v1.0 (GCF_000743615.1) Unplaced Scaffold NW_011047407.1 (783622..822474, complement)

NW_022900914.1Genomic Context describing neighboring genes Neighboring gene HEAT repeat containing 5B Neighboring gene WW domain-binding protein 2-like Neighboring gene G-patch domain containing 11 Neighboring gene sulfotransferase family 6B member 1 Neighboring gene CEBPZ opposite strand Neighboring gene CCAAT enhancer binding protein zeta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interferon-induced, double-stranded RNA-activated protein kinase
Names
Interferon-induced, double-stranded RNA-activated protein kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Fukomys damarensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference DMR_v1.0_HiC Primary Assembly

Genomic

  1. NW_022900914.1 Reference DMR_v1.0_HiC Primary Assembly

    Range
    16983883..17023457 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010611407.3 → XP_010609709.2  interferon-induced, double-stranded RNA-activated protein kinase isoform X3

    Conserved Domains (3) summary
    cd19903
    Location:51 → 118
    DSRM_EIF2AK2_rpt1; first double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cd19904
    Location:142 → 208
    DSRM_EIF2AK2_rpt2; second double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cl21453
    Location:299 → 523
    PKc_like; Protein Kinases, catalytic domain

  2. XM_010611406.3 → XP_010609708.2  interferon-induced, double-stranded RNA-activated protein kinase isoform X2

    Conserved Domains (3) summary
    cd19903
    Location:51 → 118
    DSRM_EIF2AK2_rpt1; first double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cd19904
    Location:142 → 208
    DSRM_EIF2AK2_rpt2; second double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cl21453
    Location:299 → 563
    PKc_like; Protein Kinases, catalytic domain

  3. XM_010611405.3 → XP_010609707.2  interferon-induced, double-stranded RNA-activated protein kinase isoform X1

    Conserved Domains (3) summary
    cd19903
    Location:51 → 118
    DSRM_EIF2AK2_rpt1; first double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cd19904
    Location:142 → 208
    DSRM_EIF2AK2_rpt2; second double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cl21453
    Location:299 → 563
    PKc_like; Protein Kinases, catalytic domain

  4. XM_010611408.3 → XP_010609710.1  interferon-induced, double-stranded RNA-activated protein kinase isoform X5

    Related
    ENSFDAP00000017502.1
    Conserved Domains (3) summary
    smart00220
    Location:236 → 491
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    smart00358
    Location:74 → 134
    DSRM; Double-stranded RNA binding motif
    cl21453
    Location:229 → 493
    PKc_like; Protein Kinases, catalytic domain

  5. XM_033763552.1 → XP_033619443.1  interferon-induced, double-stranded RNA-activated protein kinase isoform X4

    Conserved Domains (3) summary
    cd19904
    Location:62 → 128
    DSRM_EIF2AK2_rpt2; second double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cl00054
    Location:4 → 38
    DSRM_SF; double-stranded RNA binding motif (DSRM) superfamily
    cl21453
    Location:219 → 483
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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