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TRAF2 TNF receptor associated factor 2 [ Haliaeetus leucocephalus (bald eagle) ]

Gene ID: 104829986, updated on 3-Aug-2024

Summary

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Gene symbol
TRAF2
Gene description
TNF receptor associated factor 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Haliaeetus leucocephalus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Accipitrimorphae; Accipitriformes; Accipitridae; Accipitrinae; Haliaeetus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
100 current Haliaeetus_leucocephalus-4.0 (GCF_000737465.1) Unplaced Scaffold NW_010972619.1 (374502..399261, complement)

NW_010972619.1Genomic Context describing neighboring genes Neighboring gene complement C8 gamma chain Neighboring gene F-box and WD repeat domain containing 5 Neighboring gene endothelial differentiation related factor 1 Neighboring gene MAM domain containing 4 Neighboring gene phosphohistidine phosphatase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_010972619.1 Unplaced Scaffold Reference Haliaeetus_leucocephalus-4.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Haliaeetus leucocephalus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Haliaeetus_leucocephalus-4.0

Genomic

  1. NW_010972619.1 Reference Haliaeetus_leucocephalus-4.0

    Range
    374502..399261 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010564607.1 → XP_010562909.1  TNF receptor-associated factor 2

    See identical proteins and their annotated locations for XP_010562909.1

    Conserved Domains (4) summary
    pfam02176
    Location:124 → 180
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:305 → 468
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:240 → 300
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  2. XM_010564606.1 → XP_010562908.1  TNF receptor-associated factor 2

    See identical proteins and their annotated locations for XP_010562908.1

    Conserved Domains (4) summary
    pfam02176
    Location:124 → 180
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:305 → 468
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:240 → 300
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
Nucleotide Protein
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