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POLQ DNA polymerase theta [ Rhinopithecus roxellana (golden snub-nosed monkey) ]

Gene ID: 104667905, updated on 12-Mar-2024

Summary

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Gene symbol
POLQ
Gene description
DNA polymerase theta
See related
Ensembl:ENSRROG00000045280
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinopithecus roxellana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus
Orthologs
human mouse all
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Genomic context

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See POLQ in Genome Data Viewer
Location:
chromosome: 1
Exon count:
33
Annotation release Status Assembly Chr Location
101 current ASM756505v1 (GCF_007565055.1) 1 NC_044549.1 (42338086..42479246, complement)
100 previous assembly Rrox_v1 (GCF_000769185.1) Unplaced Scaffold NW_010810904.1 (98538..210748, complement)

Chromosome 1 - NC_044549.1Genomic Context describing neighboring genes Neighboring gene nucleosome assembly protein 1-like 1 Neighboring gene immunoglobulin-binding protein 1 pseudogene Neighboring gene syntaxin binding protein 5L Neighboring gene small nucleolar RNA U13 Neighboring gene arginine-fifty homeobox

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-directed DNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via alternative nonhomologous end joining IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA polymerase theta
Names
polymerase (DNA directed), theta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhinopithecus roxellana Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM756505v1 Primary Assembly

Genomic

  1. NC_044549.1 Reference ASM756505v1 Primary Assembly

    Range
    42338086..42479246 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030941682.1 → XP_030797542.1  DNA polymerase theta isoform X2

    UniProtKB/TrEMBL
    A0A2K6RUE6
    Conserved Domains (3) summary
    cd08638
    Location:1916 → 2379
    DNA_pol_A_theta; DNA polymerase theta is a low-fidelity family A enzyme implicated in translesion synthesis and in somatic hypermutation
    COG1204
    Location:14 → 658
    BRR2; Replicative superfamily II helicase [Replication, recombination and repair]
    cl10012
    Location:1725 → 1910
    DnaQ_like_exo; DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily

  2. XM_010370508.2 → XP_010368810.2  DNA polymerase theta isoform X1

    UniProtKB/TrEMBL
    A0A2K6RUE6
    Conserved Domains (4) summary
    cd08638
    Location:2093 → 2587
    DNA_pol_A_theta; DNA polymerase theta is a low-fidelity family A enzyme implicated in translesion synthesis and in somatic hypermutation
    COG1204
    Location:82 → 835
    BRR2; Replicative superfamily II helicase [Replication, recombination and repair]
    cd18026
    Location:82 → 295
    DEXHc_POLQ-like; DEXH-box helicase domain of DNA polymerase theta
    cl10012
    Location:1902 → 2087
    DnaQ_like_exo; DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily
Nucleotide Protein
Heading Accession and Version

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