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CAPN3 calpain 3 [ Antrostomus carolinensis (chuck-will's-widow) ]

Gene ID: 104532886, updated on 3-Aug-2024

Summary

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Gene symbol
CAPN3
Gene description
calpain 3
Locus tag
N321_13227
Gene type
protein coding
RefSeq status
MODEL
Organism
Antrostomus carolinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Strisores; Caprimulgiformes; Caprimulgidae; Antrostomus
Also known as
Calpain-3
Orthologs
human mouse all
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Genomic context

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See CAPN3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
101 current ASM70074v1 (GCF_000700745.1) Unplaced Scaffold NW_010296240.1 (29693..59782)

NW_010296240.1Genomic Context describing neighboring genes Neighboring gene glucosidase alpha, neutral C Neighboring gene zinc finger protein 106

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_010296240 Unplaced Scaffold Reference ASM70074v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Antrostomus carolinensis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM70074v1

Genomic

  1. NW_010296240.1 Reference ASM70074v1

    Range
    29693..59782
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010178204.2 → XP_010176506.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A094K6H4
    Conserved Domains (6) summary
    cd00051
    Location:687 → 741
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00648
    Location:70 → 409
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:423 → 573
    Calpain_III; Calpain large subunit, domain III
    pfam13499
    Location:718 → 774
    EF-hand_7; EF-hand domain pair
    pfam16648
    Location:577 → 643
    Calpain_u2; Unstructured region on Calpain-3
    cl08302
    Location:718 → 807
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  2. XM_029087527.1 → XP_028943360.1  calpain-3 isoform X2

    UniProtKB/TrEMBL
    A0A094K6H4
    Conserved Domains (4) summary
    pfam16648
    Location:577 → 642
    Calpain_u2; Unstructured region on Calpain-3
    cd16190
    Location:642 → 810
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:70 → 409
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:430 → 573
    Calpain_III; Calpain large subunit, domain III

  3. XM_010178205.2 → XP_010176507.1  calpain-3 isoform X3

    UniProtKB/TrEMBL
    A0A094K6H4
    Conserved Domains (5) summary
    COG5126
    Location:476 → 624
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cd00051
    Location:600 → 654
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00648
    Location:70 → 362
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:376 → 526
    Calpain_III; Calpain large subunit, domain III
    pfam13499
    Location:631 → 687
    EF-hand_7; EF-hand domain pair
Nucleotide Protein
Heading Accession and Version

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