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ALOX5 arachidonate 5-lipoxygenase [ Tyto alba (common barn owl) ]

Gene ID: 104365651, updated on 3-Aug-2024

Summary

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Gene symbol
ALOX5
Gene description
arachidonate 5-lipoxygenase
Gene type
protein coding
RefSeq status
MODEL
Organism
Tyto alba
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Strigiformes; Tytonidae; Tyto
Orthologs
human mouse all
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Genomic context

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See ALOX5 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current T.alba_DEE_v4.0 (GCF_018691265.1) Unplaced Scaffold NW_024881261.1 (21815627..21850138)
100 previous assembly ASM68720v1 (GCF_000687205.1) Unplaced Scaffold NW_010016928.1 (7667..32032)

NW_024881261.1Genomic Context describing neighboring genes Neighboring gene zinc finger AN1-type containing 4 Neighboring gene membrane associated ring-CH-type finger 8 Neighboring gene cytochrome P450 2H1 Neighboring gene biogenesis of lysosomal organelles complex 1 subunit 2 Neighboring gene broad substrate specificity ATP-binding cassette transporter ABCG2-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 5-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
polyunsaturated fatty acid 5-lipoxygenase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tyto alba Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T.alba_DEE_v4.0

Genomic

  1. NW_024881261.1 Reference T.alba_DEE_v4.0

    Range
    21815627..21850138
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042787644.1 → XP_042643578.1  polyunsaturated fatty acid 5-lipoxygenase isoform X2

    Conserved Domains (2) summary
    PLN02337
    Location:153 → 513
    PLN02337; lipoxygenase
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...

  2. XM_042787113.1 → XP_042643047.1  polyunsaturated fatty acid 5-lipoxygenase isoform X1

    Conserved Domains (2) summary
    PLN02337
    Location:153 → 674
    PLN02337; lipoxygenase
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
Nucleotide Protein
Heading Accession and Version

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