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PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing [ Opisthocomus hoazin ]

Gene ID: 104339672, updated on 3-Aug-2024

Summary

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Gene symbol
PIKFYVE
Gene description
phosphoinositide kinase, FYVE-type zinc finger containing
Locus tag
N306_10184
Gene type
protein coding
RefSeq status
MODEL
Organism
Opisthocomus hoazin
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Opisthocomiformes; Opisthocomidae; Opisthocomus
Orthologs
human mouse all
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Genomic context

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See PIKFYVE in Genome Data Viewer
Location:
chromosome: Un
Exon count:
41
Annotation release Status Assembly Chr Location
100 current ASM69207v1 (GCF_000692075.1) Unplaced Scaffold NW_009900393.1 (1499882..1564259)

NW_009900393.1Genomic Context describing neighboring genes Neighboring gene shugoshin-like 2 Neighboring gene isocitrate dehydrogenase (NADP(+)) 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_009900393.1 Unplaced Scaffold Reference ASM69207v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-phosphate 5-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 3-phosphate 5-kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Opisthocomus hoazin Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69207v1

Genomic

  1. NW_009900393.1 Reference ASM69207v1

    Range
    1499882..1564259
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009945856.1 → XP_009944158.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X1

    UniProtKB/TrEMBL
    A0A091VQS2
    Conserved Domains (4) summary
    cd00139
    Location:1790 → 2103
    PIPKc; Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment includes type II ...
    cd03334
    Location:619 → 879
    Fab1_TCP; TCP-1 like domain of the eukaryotic phosphatidylinositol 3-phosphate (PtdIns3P) 5-kinase Fab1. Fab1p is important for vacuole size regulation, presumably by modulating PtdIns(3,5)P2 effector activity. In the human homolog p235/PIKfyve deletion of this ...
    cd04448
    Location:358 → 439
    DEP_PIKfyve; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in fungal RhoGEF (GDP/GTP exchange factor) PIKfyve-like proteins. PIKfyve contains N-terminal Fyve finger and DEP domains, a central chaperonin-like domain and a C-terminal PIPK (phosphatidylinositol ...
    cd15725
    Location:155 → 216
    FYVE_PIKfyve_Fab1; FYVE domain found in metazoan PIKfyve, fungal and plant Fab1, and similar proteins

  2. XM_009945857.1 → XP_009944159.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X2

    UniProtKB/TrEMBL
    A0A091VQS2
    Conserved Domains (4) summary
    cd00139
    Location:1782 → 2095
    PIPKc; Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment includes type II ...
    cd03334
    Location:619 → 879
    Fab1_TCP; TCP-1 like domain of the eukaryotic phosphatidylinositol 3-phosphate (PtdIns3P) 5-kinase Fab1. Fab1p is important for vacuole size regulation, presumably by modulating PtdIns(3,5)P2 effector activity. In the human homolog p235/PIKfyve deletion of this ...
    cd04448
    Location:358 → 439
    DEP_PIKfyve; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in fungal RhoGEF (GDP/GTP exchange factor) PIKfyve-like proteins. PIKfyve contains N-terminal Fyve finger and DEP domains, a central chaperonin-like domain and a C-terminal PIPK (phosphatidylinositol ...
    cd15725
    Location:155 → 216
    FYVE_PIKfyve_Fab1; FYVE domain found in metazoan PIKfyve, fungal and plant Fab1, and similar proteins
Nucleotide Protein
Heading Accession and Version

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